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Tonight we answered 2 EMQs on haemophilia A and discussed 4 essay plans.
EMQ. Haemophilia A. Two
questions.
EMQ1.
Lead-in.
The following scenarios relate to haemophilia A, factor
VIII deficiency (HA).
For each, select the most appropriate answer from the option list.
Each option can be used once, more than once or not at
all.
Scenario 1.
A woman attends for
pre-pregnancy counselling. Her brother has haemophilia A. What is her risk of
being a carrier?
Scenario 2 .
A woman attends for
pre-pregnancy counselling. Her father has haemophilia A. What is her risk of
being a carrier?
Scenario 3.
If she is tested and found to
be a carrier, what tests will you arrange for her partner?
Scenario 4.
If she is a carrier, what is
the risk to her male offspring?
Scenario 5.
If she is a carrier, what is
the risk to her female offspring?
Scenario 6.
If she is a carrier and her partner has haemophilia A,
what are the risks to their female offspring?
Scenario 7.
If she is a carrier and her
partner has haemophilia A, what are the risks to their male offspring?
EMQ2. Haemophilia
A. Pre-pregnancy counselling.
Lead-in.
The following scenarios relate to haemophilia A and
pre-pregnancy counselling.
For each, select the most appropriate risk from the
option list.
Pick one option from the option list.
Each option can be used once, more than once or not at
all.
Scenario 1.
A nulliparous 20-year-old
wishes to know the risk of her being a carrier as her father has mild
haemophilia A.
Scenario 2.
A nulliparous 20-year-old wishes to know the risk of her
being a carrier as her father has severe haemophilia A.
Scenario 3.
A para 3, 30-year-old wishes to know the risk of her
being a carrier as her mother is a carrier.
Scenario 4.
A para 0+4, 25-year-old wishes to know the
risk of her being a carrier as her sister has an affected son.
Scenario 5.
A para 6,
40-year-old wishes to know the risk of her being a carrier as her daughter has
had an affected baby.
Scenario 6.
A nulliparous
woman wishes to know the risk of a son having haemophilia as she is a carrier.
Scenario 7.
A nulliparous woman wishes to know the risk of a son
having haemophilia as her husband has haemophilia A.
Scenario 8.
A nulliparous woman wishes to know the risk of a daughter
being a carrier as she is a carrier.
Scenario 9.
A nulliparous woman wishes to know the risk of a daughter
being a carrier as her husband has haemophilia A.
Scenario 10.
A nulliparous woman wishes to know the risk of a son
having haemophilia as her paternal grandfather had haemophilia A.
Scenario 11.
A nulliparous woman wishes to know the risk of a son
having haemophilia as her maternal grandfather had haemophilia A.
Scenario 12.
A nulliparous woman wishes to know the risk of a son
having haemophilia as her husband’s paternal grandfather had haemophilia A.
Scenario 13.
A nulliparous woman wishes to know the risk of a son
having haemophilia as her husband’s maternal grandfather had haemophilia A.
Scenario 14.
A nulliparous woman wishes to know the risk of a son
having haemophilia as her mother’s brother has haemophilia A.
Scenario 15.
A nulliparous woman wishes to know her risk of being a
carrier as she has read about it in a magazine. There is no family history of
haemophilia A.
Option list.
A.
|
0 %
|
B.
|
0.1 %
|
C.
|
1 %
|
D.
|
12.5 %
|
E.
|
13.3%
|
F.
|
20 %
|
G.
|
25 %
|
H.
|
33 %
|
I.
|
50 %
|
J.
|
66.6%
|
K.
|
68 %
|
L.
|
75 %
|
M.
|
80 %
|
N.
|
90 %
|
O.
|
100 %
|
P.
|
200 %
|
1. A
28-year-old woman is referred to the gynaecology clinic with suspected
premature ovarian failure. She has “hot flushes”, has not menstruated for 8
months and a FSH level was found to be 40 iu/l.
1. Outline
the main causes of premature ovarian failure. 10 marks
2.
Critically evaluate the management options. 10 marks
2. A
nulliparous woman of 30 years attends for pre-pregnancy counselling. Her father
is a carrier of the Fragile X premutation. Her paternal uncle has Fragile X
syndrome. Critically evaluate the management.
3. With
regard to endometrial cancer.
1. Outline
the key features of Type 1 and Type 2 cancers. 4
marks
2. Outline
the FIGO histological grading system. 2 marks
3.
Critically evaluate the FIGO staging for endometrial cancer. 6 marks
4. Detail
the FIGO staging system for endometrial cancer. 8 marks.
4. Critically
evaluate the statement: “fortification of flour is overdue in the UK”.
