Sunday 28 April 2024

Tutorial 29 April 2024

 29 April 2024.

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88

Jenny Myers. Tutorial. Hypertension and pregnancy

89

Role-play. Details to follow

90

SBA. ALPS study

 

88. Jenny Myers. Tutorial. Hypertension and pregnancy.

Jenny is Professor of Obstetrics & Maternal Medicine in the Maternal & Fetal Health Research Centre, University of Manchester and Consultant Obstetrician at St Mary’s, the main maternity teaching hospital in Manchester. She is an authority on hypertension in pregnancy and an outstanding teacher.

 

89. Role-play. Candidate’s instructions will be emailed shortly before the tutorial so that you have no time to prepare!

 

90. ALPS study. SBA.

These are not true SBAs as there may be >1 correct answer – saves me lots of typing!

Scenario 1. Which of the following describes the ‘ALPS’ acronym?

A

Antenatal Late Pregnancy Steroids

B

Antenatal Late Premature Steroids

C

Antenatal Late Preterm Steroids

D

Antenatal Late Preventative Steroids

E

none of the above

Scenario 2. What classification does the WHO use for preterm birth?

Option list. There is none.

Scenario 3. Which gestations were used for recruitment to ALPS?

A

32-34 weeks

B

32-36 weeks

C

33-35 weeks

D

33-36 weeks

E

34-36 weeks

F

34-37 weeks

G

none of the above

Scenario 4. Which, if any, of the following were used as criteria for “high probability of delivery in the late preterm period”?

A

preterm labour + intact membranes + cervical dilation 2 cm.

B

preterm labour + intact membranes + cervical dilation 3 cm.

C

preterm labour + intact membranes + cervical effacement > 50%

D

preterm labour + intact membranes + cervical effacement > 75%

E

preterm labour + spontaneous rupture of membranes

F

planned C section between 24 hours and 7 days later

G

planned induction of labour between 24 hours and 7 days

Scenario 5. Which, if any, of the following were the conclusions of the study?

A

betamethasone reduced the risk of neonatal respiratory complications

B

betamethasone did not reduce the risk of neonatal respiratory complications

C

betamethasone increased the risk of neonatal hyperglycaemia

D

betamethasone increased the risk of neonatal hypoglycaemia

E

betamethasone increased the risk of neonatal hypothermia

F

betamethasone increased the risk of maternal sepsis

Scenario 6. What was the purpose of the ALPS Follow Up Study?

A

to assess the risk of ADHD in children given betamethasone in the ALPS study

B

to assess the risk of Asperger’s syndrome in children given betamethasone in the ALPS study

C

to assess the risk of autism in children given betamethasone in the ALPS study

D

to assess the risk of diabetes in children given betamethasone in the ALPS study

E

to assess the risk of epilepsy in children given betamethasone in the ALPS study

F

to assess the risk of neurodevelopmental anomaly in children given betamethasone in the ALPS study

G

to assess the risk of significant sepsis in children given betamethasone in the ALPS study

Scenario 7. Which of the following details the main conclusion of the ALPS Follow Up Study?

A

the risk of the specified outcome was increased

B

the risk of the specified outcome was reduced

C

the risk of the specified outcome was unaltered

Scenario 8. What concerns were raised about the use of antenatal steroids in the paper by Yao et al in the BMJ in 2023?

A

the use of ANC increased the risk of asthma

B

the use of ANC increased the risk of eczema

C

the use of ANC increased the risk of juvenile rheumatoid arthritis

D

the use of ANC increased the risk of leukaemia

E

the use of ANC increased the risk of rickets

F

the use of ANC increased the risk of sepsis

 

 

 

Sunday 14 April 2024

15 April 2024

 

15 April 2024.

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80

Hannah Ribbans. Breech

81

Viva. Waiting list prioritisation

82

EMQ. Hepatitis D

 

80. Hannah Ribbans. Breech. Tutorial + role-play

 

81. Viva. Waiting list prioritisation.

Your consultant is away. The waiting-list manager comes to see you. The following patients have been listed by junior staff. The waiting-list manager wants you to:

confirm the appropriateness of the proposed treatment,

decide the degree of urgency,

confirm the appropriateness of the proposed venue,

decide any special requirement(s) for each patient.

Name  Age     Clinical problem                                        Proposed operation

JK

5

chronic discharge.

? foreign body

EUA

JM

32

1ry. infertility

Laparoscopy + tubal patency tests

GN

77

Vulval cancer. Coronary thrombosis x 2. Unstable angina.

Radical vulvectomy agreed at MDT.

RU

55

PMB x1. BMI 35.

D&C.

LD

32

Menorrhagia. Fibroids. Anaemia.

Vaginal hysterectomy.

DT

22

Does not want children.

Lap. Steril.

HB

14

Unwanted pregnancy at 10/52.

TOP

JY

44

GSI.

Anterior colporrhaphy.

JS

23

Discharge. Cervical ectropion.

Diathermy to cervix.

DT

55

3 cm. ovarian mass.

Laparoscopy ? proceed to Hyst + BSO.

EV

32

CIN3.

Cone biopsy.

UW

34

Endometriosis

Laparoscopic ablation

HT

88

Cystocoele/ rectocoele/ 2nd. degree uterine prolapse

Manchester Repair.

 

KN

58

Haematuria

Cystoscopy

JW

18

Menorrhagia & copes badly with menstrual hygiene. Has Down’s syndrome. Sexually active.

Hysterectomy

TB

30

Menorrhagia. 2nd. degree uterine descent. Been sterilised. Jehovah’s witness.

Vaginal hysterectomy and repair.

BM

55

Stage Ib cancer cervix. Been discussed at MDT. For Wertheim’s hysterectomy. Factor V Leiden. VTE on Pill. On warfarin.

Wertheim’s hysterectomy.

NU

60

Recurrent rectocoele.

Posterior colporrhaphy.

 

82. Hepatitis D. Hepatitis Delta. EMQ.

Abbreviations:

HBsAg:      hepatitis B surface antigen

HBsAb:      antibody to hepatitis B surface antigen

HBV:          hepatitis B virus

HCsAg:      hepatitis C surface antigen

HDV:          hepatitis D virus; hepatitis delta virus

HEsAg:      hepatitis E surface antigen

Question 1.             Which, if any, of the following statements are true in relation to HDV? This is not a true EMQ as there may be >1 correct answer.

Option list.

A

HDV is a large DNA virus

B

HDV is a defective virus

C

HDV gains entry to human cells via the HDV receptor

D

HDV gains entry to human cells by donning a disguise and using the HBV receptor

E

HDV only flourishes when HBsAb is present

F

HDV only flourishes when HBsAg is present

G

Coi   coinfection is when HDV and another viral infection are present at the same time

H

Susu superinfection is when HDV is present in abnormally high numbers

I

HDV infection is the least serious of the viral hepatitides in relation to pregnancy

J

HDV treatment was revolutionised by analysis of the benefits of drinking bleach as suggested by Donald Trump

K

the   WHO has recommended that those who follow medical advice from Donald trump should be categorised as ‘having the DTs’.

L

HDV needs the presence of HBsAg to be a significant pathogen

M

HDV needs the presence of HCsAg to be a significant pathogen

N

HDV needs the presence of HEsAg to be a significant pathogen

O

ppe  pegylated interferon alpha is highly effective as treatment

P

m     mother-to-child transmission is mainly via the placenta

Q

         WHO recommends tenofovir prophylaxis from 28 weeks in pregnancy in HDV infected women

R

the   infected neonate should be given HDV vaccine