Thursday 14 July 2016

Tutorial 14th. July 2014


14 July 2016.

Website.

34
EMQ. Surrogacy
35
EMQ. Chickenpox & pregnancy
36
EMQ. Appendicitis & pregnancy
37
EMQ. Down’s syndrome
38
Roleplay. Communication skills.

34.   EMQ. Surrogacy.
Abbreviations.
ART:           assisted reproductive technology
CF:              commissioning father
CM:            commissioning mother
CPs:            commissioning parents
PO:             parental order
SM:             surrogate mother
SSAEW:      Surrogacy Supervisory Authority England and Wales.
Option List.
a)      CM
b)      CF
c)       CPs
d)      SM
e)      Chairman of the HFEA
f)        Senior judge at the Children and Family Court
g)       traditional surrogacy
h)      gestational surrogacy
i)        HFEA
j)        SSAEW
k)       RCOG Surrogacy Sub-Committee
l)        false
m)    true
n)      none of the above
Scenario 1
List the different types of surrogacy.
Scenario 2.
“Gestational” surrogacy has better “take-home-baby” rates than “traditional” surrogacy. True/False
Scenario 3.
There are approximately 1,000 surrogate pregnancies per annum in the UK. True/False
Scenario 4.
Which national body regulates surrogacy in England?
Scenario 5.
Privately-arranged surrogate pregnancies are illegal and those involved are liable to up to 2 years in prison. True/False
Scenario 6.
List the risks of surrogacy.
Scenario 7.
Obstetricians are legally obliged to take the CPs’ wishes into consideration in managing pregnancy complications or problems. True / False
Scenario 8.
The psychological outcomes of surrogacy are fully understood. True/False.
Scenario 9.
The psychological outcomes of surrogacy are more severe after traditional surrogacy. True/False
Scenario 10.
Who has the right to arrange TOP if the fetus is found to have a major congenital abnormality?
Scenario 11.
A SM decides at 10 weeks that she does not wish to be pregnant and arranges to have a TOP. The CPs. hear about this and object strongly. To whom should they apply to have the TOP blocked?
Scenario 12.
A woman has hysterectomy and BSO to deal with extensive endometriosis at the age of 30. She marries two years later and her sister offers to act as surrogate. She undergoes IVF and 4 embryos are created. One is transferred and a successful pregnancy ensues. The baby is adopted by the woman and her husband. The 3 remaining embryos were frozen. Four years later the woman falls out with her sister, but finds another surrogate and wishes to proceed with another pregnancy. The sister says she does not want her eggs to be used and that the frozen embryos should not be transferred. Does the sister have the legal right to block the use of the embryos? Yes / No.
Scenario 13.
A girl born from donor sperm reaches the age of 16 and wishes to know the identity of her genetic father. Does she have the right to this information?  Yes / No.
Scenario 14.
A girl born from donor sperm reaches the age of 18 and wins a place at Oxford University to read medicine. Does she have the legal right to get the donor to contribute to her fees? Yes / No.
Scenario 15.
A PO is active from the moment it is completed and signed by the relevant parties.  True/False
Scenario 16.
A SM can change her mind at any time and keep the child, even if the egg was not hers.  True/False
Scenario 17.
The CPs can change their mind, leaving the SM as the legal mother.  True/False
Scenario 18.
A SM’s husband is the legal father until adoption is completed or a PO comes into force. True/False
Scenario 19.
A lesbian couple in a stable, co-habiting relationship can be CPs and become the legal parents of the child of a SM. True/False
Scenario 20.
CPs are likely to get faster legal status as the legal parents through application for a PO rather than applying for adoption. True/False

35.   EMQ. Chickenpox + pregnancy.
Abbreviations.
FVS:                     fetal varicella syndrome
NPV:                    negative predictive value
PPV:                    positive predictive value
VZV:                    varicella-zoster virus.
Question 1.
Lead-in  What type of virus causes chickenpox?              
Option List
A.       
avian virus
B.       
herpes virus
C.       
retrovirus
D.       
picovirus
E.        
pox virus
Question 2.
Lead-in
Which of the following best describes the chickenpox virus
Option List
A.       
DNA virus
B.       
RNA virus
C.       
Prion
D.       
All of the above
E.        
None of the above
Question 3.
Lead-in
What is the main reservoir of the chickenpox virus?
Option List
A.       
domestic chickens
B.       
chickens in battery farms
C.       
sparrows
D.       
humans
E.        
earthworms
Question 4.
Lead-in
How is the chickenpox virus spread?
Pick the option from option list that best fits.
Possible modes of spread.
A.      respiratory droplets
B.      direct contact with the fluid from the vesicles
C.      contact with fomites
D.      contact with stalactites
E.       from lavatory seats
Option List.
1.        
A
2.        
A + B
3.        
A +  C
4.        
A + B + C
5.        
A + B + C + D + E
Question 5.
Lead-in
Fomites - which of the following statements are true?
Statements.
A.       
fomites are bedclothes infested with bed bugs which can carry the chickenpox virus
B.       
“fomites” in Latin is the plural of “fomes”, the noun meaning “tinder” in English
C.       
fomites are inanimate objects that can effect the transfer of communicable diseases from the infected person to someone who is not infected
D.       
fomites are horizontal stalagmites, particularly found in the Dolomite mountains and capable of fostering the growth of viruses, including the chickenpox virus
E.        
fomites are the viral particles in vomit that form the aerosols particularly associated with the respiratory spread of viruses such as the chickenpox virus.
Option List
1.        
A + B + C + D + E
2.        
A + B + C + E
3.        
A + B + C + D
4.        
B + C + D
5.        
B + C + E
6.        
B + C
Question 6.
Lead-in
Which of the following are listed in GTG13 as examples of fomites?
A.      bathtubs used by person with chickenpox at the infectious stage
B.      bedding
C.      blood, fresh or dried, from person with chickenpox at the infectious stage
D.      clothing
E.       hair
F.       paper money
G.      skin cells
H.      viral remnants in vomit from person with chickenpox at the infectious stage
Option List
1.        
A + B + C + D + E + F + G + H
2.        
A + B + C + D + E + F
3.        
B + C + D + E + F + G
4.        
B + C + E + G
5.        
None of the above
Question 7.
Lead-in
With regard to the epidemiology of chickenpox in the UK, which of the following statements are true?
A
Chickenpox is endemic
B
Chickenpox is endemic with mini-epidemics every 3-4 years in the early part of the year
C
The main reservoir is chickens, particularly those that are reared intensively
D
The main reservoir is human sensory nerve root ganglia after primary infection
E
The main reservoir is fomites
Option List
1
A
3
A + C
4
A + D
5
A + E
2
B
6
B + C
7
B + C + D + E
7
B + C + D + E
Question 8
Lead-in
What proportion of the ante-natal population of the UK is immune to chickenpox?
Option List
A.       
   50%
B.       
   60%
C.       
   70%
D.       
   80%
E.        
   90%
F.        
≥ 90%

Question 9.
Lead-in
Which population of immigrant women is least likely to have immunity to chickenpox?
Option List
A.       
Middle-Eastern
B.       
Those from Antarctica
C.       
Those from the EEC
D.       
Those from tropical and sub-tropical Africa
E.        
One-eyed Mongolians with the bad habit of spitting in public
Question 10.
Lead-in
What is the incidence of chickenpox in pregnancy in the UK?
Option List
A.       
1 in 1,000
B.       
3 in 1,000
C.       
5 in 1,000
D.       
8 in 1,000
E.        
14 in 1,000
F.        
20 in 1,000
Question 11.
Lead-in
What is the usual presentation of chickenpox in a child?
Option List
A.       
Mild fever with malaise  then vesicles which appear after 2 days and  disappear after 4 – 5 days
B.       
Mild fever with malaise  then vesicles which appear after 2 days and  disappear after about 7 days
C.       
Mild fever, malaise, pruritic maculopapules that develop into vesicles and normally crust over within 5 days
D.       
Mild fever, malaise, pruritic maculopapules that develop into vesicles and normally crust over within 7 days
E.        
Mild fever, malaise, pruritic maculopapules that develop into vesicles and normally crust over within 10 days
Question 12.
Lead-in
What is the duration of infectivity after primary infection?
Option List
A.       
From the onset of fever until 48 hours after the vesicles form
B.       
From the onset of fever until 5 days after the vesicles form
C.       
From 48 hours before the development of the vesicles until 5 days later.
D.       
From 48 hours before the development of the vesicles until they crust over
E.        
From the development of the vesicles until 5 days later.
F.        
From the development of the vesicles until they crust over
Question 13.
Lead-in
A woman books at 8 weeks. Her 6-year-old son lives with her and has recently developed chickenpox? She is tested and found to be non-immune. What is her risk of infection from the domestic contact with her son?
Option List
A.       
50%
B.       
60%
C.       
70%
D.       
80%
E.        
90%
Question 14.
Lead-in
Which of the following contacts with a case of chickenpox would be significant?
        I.            contact with the mother of a child who has just developed the typical chickenpox rash
      II.            contact with the mother of a child who has not developed the typical chickenpox rash
    III.            a four-hour journey on a school bus with 20 children, one of whom develops the typical chickenpox rash the next day
    IV.            having a coffee with a neighbour who is having chemotherapy and has just developed shingles
      V.            visiting a neighbour who has developed ophthalmic shingles and has been admitted to an old-fashioned 20-bed ward
    VI.            having a coffee with an 80-year-old  neighbour who is in good health but has just had recurrence of thoracic shingles.
Option List

  1.  
all of the above

  1.  
I +  III + IV + V

  1.  
I +  III + IV + V

  1.  
II + III + IV + VI

  1.  
III + IV + V
Question 15.
Lead-in
In relation to shingles, which of the following statements are true ?
A.       
Shingles is due to reactivation of the virus which has lain dormant in the sensory nerve root ganglia
B.       
Shingles is due to reactivation of the virus which has lain dormant in the motor nerve root ganglia
C.       
Shingles is due to reactivation of the virus which has lain dormant in the autonomic nerve root ganglia
D.       
Shingles should always be regarded as infectious.
E.        
Shingles in the immuno-compromised should always be regarded as infectious.
F.        
Ophthalmic shingles should always be regarded as infections
Option List
1.        
A + D
2.        
A + E
3.        
A + E + F
4.        
B + D
5.        
C + E + F
Question 16. This is about chickenpox vaccine.
Lead-in
Which of the following statements are true? Pick the best option from the option list.
Statements.
A.      Chickenpox vaccine does not exist.
B.      Chickenpox vaccine uses a killed virus of the Okra strain.
C.      Chickenpox vaccine uses an attenuated virus of the Oka strain.
D.      All children who have not had chickenpox should be offered the vaccine after 1 year of age.
E.       Women should be screened for immune status as part of pre-pregnancy counselling or fertility treatment with ART
Option List
1.        
A.
2.        
B.
3.        
C.
4.        
B + D
5.        
B + D + E
6.        
C + D
7.        
C + D + E
8.        
None
Question 17. This relates to vaccination in early pregnancy
Lead-in
A 25-year-old woman is given varicella vaccine. Her period is due the next day, but does not occur. A pregnancy test a few days later is +ve. What should be the management?
Option List
A.       
She should be advised that there is a 5% risk of congenital varicella syndrome and be offered TOP.
B.       
She should be advised that there is a 10% risk of congenital varicella syndrome and be offered TOP.
C.       
She should be advised that the level of risk of congenital varicella syndrome after vaccination in early pregnancy is unknown and be offered TOP.
D.       
She should be advised that the level of risk of congenital varicella syndrome after vaccination in early pregnancy is unknown and be offered referral to a feto-maternal medicine expert.
E.        
She should be advised that the manufacturer has monitored occurrences of inadvertent vaccination for nearly 20 years and that no increase of the risk of congenital varicella syndrome has been identified after inadvertent vaccination in early pregnancy.
F.        
She should be advised that the vaccine contains no live virus and cannot cause fetal infection.
Question 18.
Lead-in
A woman has been referred to the booking clinic by her GP. Screening for immunity to chickenpox showed her to be seronegative. What advice would you give her?
Option List
A.       
Advise her that there is no risk unless she comes into contact with a case of chickenpox or shingles and to speak to GP or midwife if possible contact occurs..
B.       
Advise her to have the chickenpox vaccine because of the 10% risk and high mortality associated with varicella in pregnancy.
C.       
Advise her to have VZIG to reduce her risk of infection.
D.       
Advise her to take oral acyclovir until two weeks post-delivery.
E.        
None of the above.
Question 19.
Lead-in
A woman is referred to the booking clinic by her GP for urgent assessment as she was in contact with a case of chickenpox two days before. What action should be taken?
Possible actions.
        I.            take a detailed history to determine the significance of the contact and her history of and likely immunity to chickenpox.
      II.            check for VZV immunity if there is a history of a significant contact and possibility that she is not immune.
    III.            if the contact was significant and the tests for VZV immunity show her to be seronegative, offer oral acyclovir
    IV.            if the contact was significant and the tests for VZV immunity show her to be seronegative, offer VZIG.
      V.            if the contact was significant and the tests for VZV show her to be seronegative, discuss TOP.
Option List
A.       
I + II + III
B.       
I + II + III + IV
C.       
I + II + III + V
D.       
I + II  + IV
E.        
V
Question 20.
Lead-in
Which, if any, of the following statements about VZIG are correct?
        I.            VZIG is manufactured using recombinant technology
      II.            VZIG is effective in pregnancy when given within 10 days of the contact
    III.            If VZIG is given, the woman is potentially infectious for up to 28 days
    IV.            Repeat doses of VZIG should not be given in the event of repeated significant contact
      V.            There are reliable supplies of VZIG and no problems regarding availability
Option List
A.       
I + II + III
B.       
I + II + III + IV
C.       
I + II + III + IV + V
D.       
II + III
E.        
II + III + V
Question 21.
Lead-in
How does the administration of VZIG affect the duration of infectivity for the woman?
Option List
A.       
With no VZIG the woman is potentially infectious from day 8 to 28.
B.       
VZIG destroys virus and the woman is potentially infections from day 8 to 21.
C.       
VZIG does not alter the period in which the woman is potentially infections.
D.       
VZIG reduces the risk of shingles in later life
E.        
None of the above
Question 22.
Lead-in
With regard to established varicella in pregnancy, which, if any, of the following statements are true? Choose the best option from the option list.
        I.            the main risk to the mother comes from pneumonia, with an incidence of about 10%
      II.            the main risk to the mother comes from pneumonia, with an incidence of about 40%
    III.            hepatitis and encephalitis are more common compared to the non-pregnant state
    IV.            mortality from varicella pneumonia have fallen to < 15%
      V.            the death rate from varicella pneumonia is estimated to be 5 times greater than in the non-pregnant
Option List
A.       
I  + III + IV + V
B.       
II + III + IV + V
C.       
I + IV + V
D.       
II + IV + V
E.        
I + IV

Question 23.
Lead-in
A GP phones to say that a patient of his at 10 weeks’ gestation has developed the typical rash of chickenpox. Her son had proven chickenpox a couple of weeks previously. She had been tested and found to be non-immune, but declined VZIG. Which, if any of the following statements would you include in your advice to the GP.
        I.            admit the woman for assessment, VZIG and acyclovir after counselling re risks and benefits.
      II.            arrange for her to be seen in the next antenatal clinic.
    III.            advise re prevention of secondary bacterial infection of the lesions
    IV.            advise about her avoiding contact with susceptible individuals until at least 7 days after the lesions crust over
      V.            advise the GP of the criteria for hospital admission and the need for the woman to be informed of them.
    VI.            advise the GP to discuss the risks and benefits of acyclovir 800mg five times daily for seven days and to prescribe it if the woman agrees.
  VII.            advise that acyclovir is contraindicated once the rash appears
VIII.            advise that VZIG is ineffectual once the rash has appeared
Question 24.
Lead-in
What kind of drug is aciclovir?
There is no option list
Question 25.
Lead-in
How effective is aciclovir?
There is no option list.
Question 26.
Lead-in
Which, if any, of the following statements are true in relation to the diagnosis of fetal varicella syndrome?
Option List
A.       
detailed ultrasound examination by a fetal medicine expert should be offered
B.       
fetal MRI is superior to US examination and should be the 1ry test if available
C.       
amniocentesis should be offered as detection of varicella DNA makes FVS probable
D.       
amniocentesis should be done as early as possible, avoiding any varicella lesions
E.        
PCR which is –ve for varicella DNA in amniotic fluid has a strong NPV for FVS
F.        
PCR which is +ve for varicella DNA in amniotic fluid has a strong PPV for FVS
Question 27.
Lead-in
Which, if any, of the following statements are true in relation to fetal varicella syndrome?
Option List
A.       
FVS occurs in relation to 1ry. infection in-utero
B.       
FVS occurs in relation to 2ry. infection in-utero
C.       
the risk of FVS is ~ 5% when 1ry. infection in-utero  occurs < 13 weeks
D.       
the risk of FVS is ~ 10% when 1ry. infection in-utero  occurs between 13  and 20 weeks
E.        
the risk of FVS is greatest when 1ry. infection in-utero occurs within 4 weeks of birth
Question 28.
Lead-in
Which, if any, of the following statements are true in relation to administration of varicella vaccine in pregnancy.
Option List
A.       
varicella vaccine is a recombinant vaccine and licensed for use in pregnancy
B.       
varicella vaccine contains a live, attenuated vaccine and is contraindicated in pregnancy
C.       
varicella vaccine contains a live, attenuated vaccine and is safe to use after 12 weeks
D.       
varicella vaccine should not be given to women who are breastfeeding
E.        
TOP should be advised if varicella vaccine is given in the 1st. trimester
F.        
VZV immunoglobulin should be given if varicella vaccine is given in the 1st. trimester
Question 29.
Lead-in
Which, if any, of the following statements are true in relation to neonatal varicella (NV)
Option List
A.       
the risk of NV is 90% with fetal infection in the 1st. trimester
B.       
the risk of NV is 50% with fetal infection in the 2nd. trimester
C.       
the risk of NV is 10% with fetal infection in the 4 weeks before delivery
D.       
planned delivery should be delayed, if safe, until 7 days after start of the maternal rash
E.        
women with active chickenpox should not breastfeed until 10 days after the lesions crust

36.   EMQ. Topic. Appendicitis in pregnancy (AIP)
Abbreviations.
AIP
Appendicitis in pregnancy
CRP
C reactive protein
CT
computed tomography, also known as computerised tomography
RLQP
right lower quadrant pain
RUQP
right upper quadrant pain
Question 1.
Lead-in
What is the approximate incidence of appendicitis in pregnancy?
Option List
F.        
1 in 500
G.       
1 in 1,000
H.       
1 in 2,000
I.         
1 in 5,000
J.         
1 in 10,000
Question 2.
Lead-in
When is appendicitis in pregnancy most common?
Option List
A.       
first trimester
B.       
second trimester
C.       
trimester
D.       
1st. and 2nd. stages of labour
E.        
in the hours after the 3rd. stage of labour
F.        
during the puerperium
Question 3.
Lead-in
What eponymous title is given to the surface marker for the appendix?
Option List
F.        
McBarney’s point
G.       
MacBurney’s point
H.       
McBurney’s point
I.         
MacBorney’s point
J.         
McBorney’s point
Question 4.
Lead-in
Where is the point referred to in the above question?
Option List
A.       
1/3 of the way along the line joining the anterior superior iliac spine and umbilicus
B.       
1/2 of the way along the line joining the anterior superior iliac spine and umbilicus
C.       
2/3 of the way along the line joining the anterior superior iliac spine and umbilicus
D.       
1/3 of the way along the line joining the left and right anterior superior iliac spines
E.        
1/2 of the way along the line joining the left and right anterior superior iliac spines
Question 5.
Lead-in
Which, if any, of the following statements are true about the person after whom the point in the above questions is named?
Statements
A.       
he spent 2 years as a postgraduate working in Berlin, London, Paris and Vienna
B.       
he was Professor of surgery at the Roosevelt hospital, New York from 1889 to 1894
C.       
he presented his classical paper on appendicitis to the NY Surgical Society in 1889
D.       
he was a transvestite
E.        
he died of a heart attack while on a hunting trip
Question 6.
Lead-in.
Pick the best option from the list below in relation to right lower quadrant pain in AIP in the pregnant and non-pregnant.
Option List
A
comparative figures for the pregnant and non-pregnant are unknown due to the rarity of appendicitis in pregnancy
B
RLQP is as common in the pregnant as in the non-pregnant
C
RLQP is less common in the pregnant
D
RLQP is more common in the pregnant
E
RLQP is rare in pregnancy
Question 7.
Lead-in.
Pick the best option from the list below in relation to right upper quadrant pain in AIP in the pregnant and non-pregnant.
Option List
A
comparative figures for the pregnant and non-pregnant are unknown due to the rarity of appendicitis in pregnancy
B
RUQP is ½ as common in the pregnant as in the non-pregnant
C
RUQP is as common in the pregnant as in the non-pregnant
D
RUQP is twice as common in the pregnant as in the non-pregnant
E
RUQP is four times as common in the pregnant as in the non-pregnant
Question 8.
Lead-in.
Pick the best option from the list below in relation to nausea in AIP in the pregnant and non-pregnant.
Option List
A
comparative figures for the pregnant and non-pregnant are unknown due to the rarity of appendicitis in pregnancy
B
nausea is as common in the pregnant as in the non-pregnant
C
nausea is less common in the pregnant
D
nausea is more common in the pregnant
E
nausea is rare in pregnancy
Question 9.
Lead-in.
Which condition did CMACE say should be excluded in women presenting acutely with gastrointestinal symptoms?
Option List
A
aortic dissection
B
appendicitis
C
Caesarean section scar pregnancy
D
ectopic pregnancy
E
pancreatitis
F
ovarian torsion
Question 10.
Lead-in.
Pick the best option from the list below in relation to abdominal guarding in AIP in the pregnant and non-pregnant.
Option List
A
comparative figures for the pregnant and non-pregnant are unknown due to the rarity of appendicitis in pregnancy
B
abdominal guarding is as common in the pregnant as in the non-pregnant
C
abdominal guarding is less common in the pregnant
D
abdominal guarding is more common in the pregnant
E
abdominal guarding is rare in pregnancy
Question 11.
Lead-in.
Pick the best option from the list below in relation to rebound tenderness in AIP in the pregnant and non-pregnant.
Option List
A
comparative figures for the pregnant and non-pregnant are unknown due to the rarity of appendicitis in pregnancy
B
rebound tenderness is as common in the pregnant as in the non-pregnant
C
rebound tenderness is less common in the pregnant
D
rebound tenderness is more common in the pregnant
E
rebound tenderness is rare in pregnancy
Question 12.
Lead-in.
Pick the best option from the list below in relation to fever in AIP in the pregnant and non-pregnant.
Option List
A
comparative figures for the pregnant and non-pregnant are unknown due to the rarity of appendicitis in pregnancy
B
fever is as common in the pregnant as in the non-pregnant
C
fever is less common in the pregnant
D
fever is more common in the pregnant
E
fever is rare in pregnancy
Question 13.
Lead-in
How useful is the finding of leucocytosis in making the diagnosis of AIP?
Option List
G.       
sine qua non
H.       
very useful
I.         
not very useful
J.         
I don’t know
Question 14.
How useful is the finding of a raised CRP level the diagnosis of AIP?
Option List
A.       
sine qua non
B.       
very useful
C.       
not very useful
D.       
I don’t know
Question 15.
Lead-in
What are the ultrasound features of appendicitis?
Option List
A
appendix with diameter > 0.6 mm.
B
appendix with diameter > 1 cm.
C
blind-ending tubular structure
D
non-compressible tubular structure
E
none of the above
Question 16.
Lead-in
What figures do W&M give for sensitivity & specificity for US diagnosis of appendicitis?
Option List

Sensitivity
Specificity
A
≥65%
≥80%
B
≥75%
≥85%
C
≥86%
≥97%
D
≥91%
≥98%
E
≥95%
≥95%
Question 17.
Lead-in
Which, if any, of the following statements are true about CT scanning for the diagnosis of AIP?
Option List
A
CT scanning has sensitivity > 85% and specificity >95%
B
CT scanning exposes mother and fetus to radiation doses of little concern
C
CT scanning has replaced ultrasound scanning for AIP
D
CT scanning is not of proven value after inconclusive ultrasound scanning
E
CT scanning is of proven value and most useful  after inconclusive ultrasound scanning
Question 18.
Lead-in
Which, if any, of the following statements are true about MRI scanning for the diagnosis of AIP?
Option List
A
MRI scanning has sensitivity > 90% and specificity >97%
B
MRI scanning exposes mother and fetus to radiation doses of little concern
C
MRI scanning has replaced ultrasound scanning for AIP
D
MRI scanning is not of proven value after inconclusive ultrasound scanning
E
MRI scanning is of proven value and most useful  after inconclusive ultrasound scanning
Question 19
Lead-in
Which, if any, of the following statements are true about the complications of AIP?
Option List
A
fetal loss rate in uncomplicated AIP is about 1.5%
B
fetal loss rate in AIP complicated by peritonitis is about 6%
C
fetal loss rate in AIP complicated by perforation of the appendix is up to 36%
D
pre-term delivery rates increase in AIP complicated by perforation of the appendix
E
a low level of suspicion should apply to the diagnosis of AIP in relation to surgical intervention
Question 20
Lead-in
Which, if any, of the following statements are true about surgery for AIP?
Option List
A
laparotomy should be done through a grid-iron incision with the mid-point the surface marker for the appendix in the right iliac fossa
B
laparotomy should be done through a right paramedian incision starting at the level of the umbilicus
C
about 35% of laparotomies show no evidence of appendicitis
D
the appendix should be removed even if it looks normal
E
antibiotic therapy is an alternative to surgery in early cases of AIP
Question 21
Lead-in
Which, if any, of the following statements are true about surgery for AIP?
Option List
A
laparotomy should be done through a grid-iron incision with the mid-point the surface marker for the appendix in the right iliac fossa
B
laparotomy should be done through a right paramedian incision starting at the level of the umbilicus
C
about 35% of laparotomies show no evidence of appendicitis
D
the appendix should be removed even if it looks normal
E
antibiotic therapy is an alternative to surgery in early cases of acute AIP
Question 22
Lead-in
Which, if any, of the following statements are true about surgery for AIP?
Option List
A
laparoscopic appendicectomy is an acceptable alternative to laparotomy, but only in the 1st. trimester
B
laparoscopic appendicectomy is an acceptable alternative to laparotomy, but only in the 1st. & 2nd. trimesters
C
laparoscopic appendicectomy is an acceptable alternative to laparotomy, at all gestations
D
there is evidence that laparoscopic appendicectomy is associated with doubling of the rate of fetal loss

37.   EMQ.
Lead-in.
The following scenarios relate to screening for Down’s syndrome.
Pick one option from the option list. Each option can be used once, more than once or not at all.
Option list.
a.       1 in 2
b.      1 in 5
c.       1 in 10
d.      1 in 20
e.       1 in 40
f.        1 in 250
g.       1 in 400
h.      1 in 1,000
i.         5 mm.
j.         6 mm.
k.       7 mm.
l.         8 mm.
m.    10 mm.
n.      1%
o.      2%
p.      5%
q.      10%
r.        80%
s.       95%
t.        90%
u.      95%
v.       higher
w.     lower
x.       true
y.       false
z.       none of the above.
Scenario 1.
What is the age-related risk of DS at 20 years?
Scenario 2.
What is the age-related risk of DS at 30 years?
Scenario 3.
What is the age-related risk of DS at 35 years?
Scenario 4.
What is the age-related risk of DS at 40 years?
Scenario 5.
What is the age-related risk of DS at 45 years?
Scenario 6.
AFP levels are lower in Ds.
Scenario 7
Inhibin levels are raised in DS.
Scenario 8
Oestriol levels are raised in DS.
Scenario 9
β-hCG levels are raised in DS.
Scenario 10
1st. trimester PAPP-A levels are lower in DS.
Scenario 11
2nd. trimester PAPP-A levels are normal in DS.
Scenario 12
 What characteristic is described in relation to the occipital hairline in DS?
Scenario 13
 What characteristic is described in relation to the frontal hairline in DS?
Scenario 14
 What is the incidence of congenital heart anomaly in DS?
Scenario 15
 Which is the most common congenital heart anomaly in DS?
Scenario 16
 Which major haematological condition is more common in those with DS?
Scenario 17
 Which major neurological condition is more common in middle  age in those with DS?
Scenario 18
 Which spinal anomaly is more common in DS and of concern to anaesthetists?

38.   Roleplay. Communication skills: You have been asked to see a woman who is planning her first pregnancy. Her brother has cystic fibrosis. The consultant has told you to explain the mode of inheritance and the implications for her and any pregnancy.







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