Sunday, 20 August 2023

Tutorial 21st. August 2023

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29

Role-play. Freebirth.

30

Structured discussion. The uses of MgSO4 in O&G

31

Blurb. Autosomal recessive condition

32

EMQ. The MAGPIE trial 

33

EMQ. Brexanolone

 

29.      Role-play. Freebirth.

Candidate’s instructions.

You are an SpR5 in charge of the antenatal clinic as the consultant is on sick leave. Ms Jones has attended the booking clinic but the midwives don’t know what to do with her as she does not wish to be booked. They have asked you to see her. Your tasks are to deal with her as you would in real life.

GP letter.

The Health Centre,

Utopia-on-Sea.

Re Helen Jones,

287 Main Street,

Utopia-on-Sea.

 

Dear Doctor,

Ms Jones has an appointment in the booking clinic when she will be about 10 weeks advanced in her first pregnancy. She intends to have no medical or midwifery care during the pregnancy or labour and delivery, planning what she calls ‘free birth’ after reading newspaper reports about the dangers of maternity hospitals. I have not come across ‘free birth’ before and plan to speak to my medical defence body about the implications for the medical and midwifery staff at the Health Centre.

Ms. Jones wishes to attend the booking clinic, but not to book! Her wishes are to arrange screening for Down’s syndrome and she would like to have a 20-week scan to check the baby looks normal, but does not want any other involvement with the maternity department or its staff.

She is an intelligent and articulate young woman with no significant health record. Her only dealings with the Health Centre have been to have cervical smears, which have been normal, prescriptions for the Pill and treatment a couple of years ago for a badly-sprained ankle.

I shall be most appreciative of your advice in this matter. I have asked her to return to see me and the midwife after the hospital visit so that we can clarify what we can do to help her and our responsibilities in this matter, which, I am sure are going to cause the professionals with whom she has dealings a lot of head-scratching.

John Williams. FRCGP.

 

30.      Structured discussion. The uses of MgSO4 in O&G.

Candidate’s instructions.

This is a structured discussion about the uses of MgSO4 in O&G, but it is an extreme example. The examiner will not ask questions, prompt or otherwise assist. It is up to you to give as full an account of the uses as you can muster.

 

31.      Blurb. Autosomal recessive condition.

Discussion of the key facts to include in this blurb and its possible wording.

 

32.      The MAGPIE trial.

It is useful to have the basic facts to show how smart you are in a viva.

Question 1.   Which of the following is true of the Magpie trial?

Option list.

A

it compared MgSO4 with placebo in the management of eclampsia / severe PET

B

it compared MgSO4 with lytic cocktail in the management of eclampsia / severe PET

C

it compared MgSO4 with phenytoin in the management of eclampsia / severe PET

D

it compared MgSO4 with alcohol in the management of threatened premature labour

E

it compared MgSO4 with atosiban in the management of threatened premature labour

F

it compared MgSO4 with ritodrine in the management of threatened premature labour

G

it compared MgSO4 with dexamethasone in the prevention of cerebral palsy due to extreme prematurity

H

it compared MgSO4 with placebo in the prevention of cerebral palsy due to extreme prematurity

I

none of the above

Question 2.   Which if any of the following are true of the Magpie trial?

Option list.

A

it involved ~ 1,000 women

B

it involved ~ 10,000 women

C

it involved ~ 20,000 women

C

it involved > 20,000 women

D

it involved ~ 30 hospitals

E

it involved ~ 50 hospitals

F

it involved ~ 80 hospitals

G

it involved > 150 hospitals

H

it involved 5 countries

I

it involved 10 countries

J

it involved 20 countries

K

it involved 30 countries

L

it involved 50 countries

M

it involved >50 countries

Question 3.   Which if any of the following are true?

Option list.

A

almost 50% of the women were in Africa

B

almost 50% of the women were in America

C

almost 50% of the women were in Asia

D

almost 50% of the women were in Australia / New Zealand

E

almost 50% of the women were in Europe

Question 4.   Which, if any, of the following is true of the Magpie trial?

Option list.

A

cerebral palsy rates at 2 years were ↓ by the use of MgSO4 in babies born < 34 weeks

B

cerebral palsy rates at 2 years were unchanged  by the use of MgSO4 in babies born < 34 week

C

eclampsia rates were reduced by about half by the use of MgSO4

D

eclampsia rates were reduced by about half by the use of MgSO4 but only in underdeveloped countries

E

maternal mortality was significantly ↓ by the use of MgSO4

F

maternal mortality was significantly ↓ by the use of MgSO4, but only in underdeveloped countries

G

premature delivery was significantly ↓ by the use of MgSO4

H

perinatal mortality from prematurity was significantly ↓ by the use of MgSO4

 

33.      Brexanolone.

Abbreviations.

GABAA: γ-aminobutyric acid type A.

Scenario 1.    Which, if any, of the following statements are true?

Option list.

A

Brexanolone it is a water soluble form of allopregnanolone

B

allopregnanolone is an oestrogen metabolite and levels mirror those of oestrogen

C

allopregnanolone is a potent modulator of GABAA receptors in the brain

D

brexanolone is effective in the treatment of postpartum depression

E

brexanolone is administered orally

F

brexanolone is licensed for use in the UK

 

 


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