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MRCOG tutorial 9th. December 2024

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9 December 2024.                                        

   

36

SBA. Appendicitis in pregnancy

37

SBA. Pertussis and pregnancy

38

SBA. Placenta accreta, increta & percreta

39

EMQ. Cervical cancer staging

40

EMQ. Headache

                                                                                                    

36.   Appendicitis in pregnancy.

Abbreviations.

AIP:       appendicitis in pregnancy

CRP :     C reactive protein

EFHRM: electronic fetal heart rate monitoring

RLQP:    right lower quadrant pain

RUQP:   right upper quadrant pain

 

Question  1.      What is the approximate incidence of appendicitis in pregnancy?

A

1 in 500

B

1 in 1,000

C

1 in 2,000

D

1 in 5,000

E

1 in 10,000

Question  2.      Is appendicitis more or less common in pregnancy?

A

just as common

B

less common

C

maybe

D

more common

E

no one knows

F

no one cares

Question  3.      How is maternal death from appendicitis classified?

A

coincidental death

B

direct death

C

incidental death

D

indirect death

E

none of the above

Question  4.      When is appendicitis in pregnancy most common?

A

first trimester

B

second trimester

C

trimester

D

1st. and 2nd. stages of labour

E

in the hours after the 3rd. stage of labour

 

during the puerperium

Question  5.           What eponymous title is given to the surface marker for the appendix?

A

McBarney’s point

B

MacBurney’s point

C

McBurney’s point

D

MacBorney’s point

E

McBorney’s point

Question  6.      Where is the point referred to in the above question?

A

1/3 of the way along the line joining the anterior superior iliac spine and umbilicus

B

1/2 of the way along the line joining the anterior superior iliac spine and umbilicus

C

2/3 of the way along the line joining the anterior superior iliac spine and umbilicus

D

1/3 of the way along the line joining the left and right anterior superior iliac spines

E

1/2 of the way along the line joining the left and right anterior superior iliac spines

Question  7.      Which, if any, of the following statements are true about the person after whom the

point in the above questions is named?

A

he spent 2 years as a postgraduate working in Berlin, London, Paris and Vienna

B

he was Professor of surgery at the Roosevelt hospital, New York from 1889 to 1894

C

he presented his classical paper on appendicitis to the NY Surgical Society in 1889

D

he was a transvestite

E

he died of a heart attack while on a hunting trip

Question  8.      Pick the best option from the list below in relation to right lower quadrant pain in

AIP.

A

comparative figures for the pregnant and non-pregnant are unknown

B

RLQP is as common in the pregnant as in the non-pregnant

C

RLQP is less common in the pregnant

D

RLQP is more common in the pregnant

E

RLQP is rare in pregnancy

Question  9.      Pick the best option from the list below in relation to right upper quadrant pain in

AIP.

A

comparative figures for the pregnant and non-pregnant are unknown

B

RUQP is ½ as common in the pregnant as in the non-pregnant

C

RUQP is as common in the pregnant as in the non-pregnant

D

RUQP is twice as common in the pregnant as in the non-pregnant

E

RUQP is four times as common in the pregnant as in the non-pregnant

Question  10.  Pick the best option from the list below in relation to nausea in AIP.

A

comparative figures for the pregnant and non-pregnant are unknown

B

nausea is as common in the pregnant as in the non-pregnant

C

nausea is less common in the pregnant

D

nausea is more common in the pregnant

E

nausea is rare in pregnancy

Question  11.  Which condition did CMACE say should be excluded in women presenting acutely

with gastrointestinal symptoms?

A

aortic dissection

B

appendicitis

C

Caesarean section scar pregnancy

D

ectopic pregnancy

E

pancreatitis

F

ovarian torsion

Question  12.  Pick the best option from the list below in relation to abdominal guarding in AIP.

A

comparative figures for the pregnant and non-pregnant are unknown

B

abdominal guarding is as common in the pregnant as in the non-pregnant

C

abdominal guarding is less common in the pregnant

D

abdominal guarding is more common in the pregnant

E

abdominal guarding is rare in pregnancy

Question  13.  Pick the best option from the list below in relation to rebound tenderness in AIP.

A

comparative figures for the pregnant and non-pregnant are unknown

B

rebound tenderness is as common in the pregnant as in the non-pregnant

C

rebound tenderness is less common in the pregnant

D

rebound tenderness is more common in the pregnant

E

rebound tenderness is rare in pregnancy

Question  14.  Pick the best option from the list below in relation to fever in AIP.

A

comparative figures for the pregnant and non-pregnant are unknown

B

fever is as common in the pregnant as in the non-pregnant

C

fever is less common in the pregnant

D

fever is more common in the pregnant

E

fever is rare in pregnancy

Question  15.  How useful is the finding of leucocytosis in making the diagnosis of AIP?

A

sine qua non

B

very useful

C

not very useful

D

I don’t know

E

none of the above

Question  16.  How useful is the finding of a raised CRP level in the diagnosis of AIP?

A

sine qua non

B

very useful

C

not very useful

D

I don’t know

E

none of the above

Question  17.  What are the ultrasound features of appendicitis?

A

appendix with diameter > 6 mm.

B

appendix with diameter > 1 cm.

C

blind-ending tubular structure

D

non-compressible tubular structure

E

none of the above

Question  18.  What do W&M give for sensitivity & specificity for US diagnosis of appendicitis?

 

Sensitivity

Specificity

A

≥65%

80%

B

≥75%

≥85%

C

≥86%

≥97%

D

≥91%

≥98%

E

≥95%

≥95%

Question  19.  Which, if any, of the following are true about CT scanning for the diagnosis of AIP?

A

CT scanning has sensitivity > 85% and specificity >95%

B

CT scanning exposes mother and fetus to radiation doses of little concern

C

CT scanning has replaced ultrasound scanning for AIP

D

CT scanning is not of proven value after inconclusive ultrasound scanning

E

CT scanning is of proven value and most useful after inconclusive ultrasound scanning

Question  20.  Which, if any, of the following statements are true about MRI scanning for the

diagnosis of AIP?

A

MRI scanning has sensitivity > 90% and specificity >97%

B

MRI scanning exposes mother and fetus to radiation doses of little concern

C

MRI scanning has replaced ultrasound scanning for AIP

D

MRI scanning is not of proven value after inconclusive ultrasound scanning

E

MRI scanning is of proven value and most useful after inconclusive ultrasound scanning

Question  21.  Which, if any, of the following statements are true about the complications of AIP?

A

bowel obstruction

B

longer inpatient stay

C

pneumonia sepsis and septic shock

D

postoperative infection

E

ureteric damage

F

none of the above

Question  22.         Which, if any, of the following statements are true about the complications of AIP?

A

fetal loss rate in uncomplicated AIP is about 1.5%

B

fetal loss rate in AIP complicated by peritonitis is about 6%

C

fetal loss rate in AIP complicated by perforation of the appendix is up to 36%

D

pre-term delivery rates increase in AIP complicated by perforation of the appendix

E

none of the above

Question  23.  Which, if any, of the following statements are true about surgery for AIP?

A

conservative management is linked to a greater incidence of complications

B

laparotomy should be done through a grid-iron incision with the mid-point the surface marker for the appendix in the right iliac fossa

C

laparotomy should be done through a right paramedian incision starting at the level of the umbilicus

D

about 35% of laparotomies show no evidence of appendicitis

E

the appendix should be removed even if it looks normal

F

antibiotic therapy is an alternative to surgery in early cases of acute AIP

Question  24.  Which, if any, of the following statements are true about surgery for AIP?

A

laparoscopic appendicectomy is an acceptable alternative to laparotomy, but only in the 1st. trimester

B

laparoscopic appendicectomy is an acceptable alternative to laparotomy, but only in the 1st. & 2nd. trimesters

C

laparoscopic appendicectomy is an acceptable alternative to laparotomy, at all gestations

D

there is evidence that laparoscopic appendicectomy is associated with doubling of the rate of fetal loss

E

none of the above

Question  25.  Which, if any, of the following statements are true about C section in relation to AIP?

A

C section is rarely necessary

B

C section increases the risk of uterine infection if peritonitis is present

C

C section should be offered if elective C section is planned

D

C section should be considered if the woman is critically ill

Question  26.  Which, if any, of the following statements are true about the fetal heart rate?

A

EFHRM should be done pre and post-operatively in surgery for AIP

B

EFHRM should always be done intra-operatively in surgery for AIP

C

the drugs used for GA tend to cause fetal tachycardia

D

the drugs used for GA commonly cause a sinusoidal pattern

E

C section should be done if abnormal EFHRM patterns occur

F

fetal scalp pH sampling should be done if abnormal EFHRM patterns occur

G

fetal blood sampling should be done if abnormal EFHRM patterns occur

 

TOG questions. These are open access, so reproduced here.

Appendicitis is a likely diagnosis in pregnancy when,

1.     ultrasound shows a non-compressible blind-ending tube in the right iliac fossa measuring 10 mm in diameter.                                                                                                 False / True

2.     a patient presents with right-sided abdominal pain, constipation and malaise. False / True

In the diagnosis of appendicitis in pregnancy,

3.     ultrasound is the best method for imaging in a morbidly obese patient.      False / True

4.     MRI has the greatest specificity of all imaging modalities.                         False / True

With regard to the management of a pregnant patient with appendicitis,

5.     it should be operative if the diagnosis is certain.                                         False / True

6.     it should primarily aim to reduce any delay in surgical intervention.       False / True

7.     it should not involve appendicectomy if the appendix appears normal at the time of surgery.

                                                                                                                                        False / True

8.     it should include delivery of the fetus regardless of gestation if the patient is critically ill.

                                                                                                                                        False / True

9.     some cases may be treated with antibiotics alone.                                     False / True

General anaesthesia for pregnant women undergoing appendicetomy,

10.   carries ~ a 25-fold increased risk of complications than regional anaesthesia. False / True

11.   has temporary effects on the fetus as all induction and maintenance agents cross the placenta.

                                                                                                                                        False / True

12.   has a uterotonic effect.                                                                                     False / True

Surgery for appendicetomy in pregnancy,

13.   increases the rate of miscarriage.                                                                    False / True

14.   has the lowest risk to the fetus when performed in the second trimester. False / True

15.   should be delayed until antenatal corticosteroids are given (in the absence of severe maternal sepsis) if the gestation is critical.                                                                            False / True

Concerning acute appendicitis in pregnancy,

16.   it is the most common cause of acute surgical abdomen.                          False / True

17.   it most commonly occurs in the first trimester.                                            False / True

18.   it has a fetal loss rate exceeding 50% if the appendix perforates.            False / True

With regard to imaging as an investigation for appendicitis in pregnancy,

19.   the primary goal is to rule out differential diagnoses.                                 False / True

20.   the secondary goal is to reduce the negative appendicectomy rate.       False / True

 

37.   Pertussis and pregnancy.

Abbreviations.

JCVI:   Joint Committee on Vaccination and Immunisation .

PIPP:  pertussis immunisation programme for pregnancy.

Question  1.      Why is pertussis of current concern in obstetrics?

A

Research has linked pertussis in the 1st. trimester to risk of congenital heart disease

B

A mini-epidemic since 2011 has caused deaths of mothers & of babies < 3 months

C

A mini-epidemic since 2011 has caused deaths of babies < 3 months

D

The infecting organism has become increasingly drug-resistant

E

The infecting organism has become increasingly virulent

Question  2.      Which organism causes whooping cough?

A

Bordella pertussis

B

Bacteroides pertussis

C

Rotavirus whoopoe

D

Respiratory syncytiovirus pertussis

E

None of the above

Question  3.           Which, if any, of the following statements are true about the organism what causes whooping cough? This is not a true SBA as I have condensed several questions into one to save space and there may be more than one correct answer.

A

the organism is aerobic

B

the organism is anaerobic

C

the organism is capsulated

D

the organism is flagellate

E

the organism is an obligate intra-cellular parasite

F

the organism is a Gram -ve diplococcus

G

the organism is a Gram +ve diplococcus

H

the organism requires special transport media

I

no one is going to ask me any of this stuff


Question  4.           Which of the following statements is true?

A

Pertussis is no longer a significant threat to infants

B

Pertussis remains a significant threat to infants

C

The risk of death from pertussis is eliminated by timely antibiotic therapy

D

the risk of death from pertussis is eliminated by timely antiviral therapy

E

None of the above

Question  5.      Which of the following statements is true?

A

Pertussis is not a notifiable disease

B

Pertussis is a notifiable disease

C

Pertussis is not a notifiable disease, but cases should be reported to the local bacteriologist

D

Pertussis is not a notifiable disease, but cases should be subject to audit

Question  6.      What is the main mode of spread of the organism that causes pertussis?

A

contact with contaminated surfaces

B

contaminated food

C

contaminated water

D

respiratory droplets

E

none of the above

Question  7.           What is the main reservoir of the organism that causes pertussis?

A

budgerigars

B

cats

C

dogs

D

humans

E

pigeons

F

pigs

G

none of the above

Question  8.      What is the epidemiology of pertussis?

A

the condition is endemic

B

the condition is endemic with mini-epidemics every 3-5 years

C

the condition is endemic with mini-epidemics most years in the winter months

D

the condition is epidemic, with outbreaks at roughly three-year intervals

E

the condition is epidemic, with outbreaks at unpredictable intervals

Question  9.           What is the incubation period for pertussis?

A

3-6     days

B

7-10   days

C

11-14 days

D

15-18 days

E

none of the above.

Question  10.        What is the duration of infectivity of someone with pertussis?

A

2 days from exposure → 5 days after onset of paroxysms of coughing

B

3 days from exposure → 10 days after onset of paroxysms of coughing

C

4 days from exposure → 14 days after onset of paroxysms of coughing

D

6 days from exposure → 21 days after onset of paroxysms of coughing

E

none of the above

Question  11.        What % of non-immune, close contacts of pertussis will develop the disease?

A

50%

B

60%

C

70%

D

80%

E

90%

Question  12.        Which of the following best describe the DOH’s advice about pertussis? This is not a true SBA as there may be > 1 connect answer.

A

The DOH advises that all pregnant women be immunised to maternal death rates.

B

The DOH advises that all pregnant women be immunised to deaths in babies < 3 months.

C

The DOH advises that all babies be immunised at birth.

D

The DOH advised that “Boostrix- IPV should replace “Repevax” from July 2014.

E

The DOH advises that immunisation of pregnant women be continued permanently

Question  13.        Which, if any, of the following statements is true in relation to average annual number of deaths due to pertussis in the years before routine child immunisation was introduced?

A

the number was 10,000

B

the number was    5,000

C

the number was    4,000

D

the number was    3,500

E

the number was    1,000

Question  14.  Which, if any, of the following statements are true in relation to pertussis vaccine.

A

Boostrix- IPV” is a vaccine for pertussis only

B

“Repevax” is a vaccine for pertussis only

C

Boostrix- IPV” & “Repevax” are live, attenuated vaccines

D

Boostrix- IPV” & “Repevax” act against diphtheria, tetanus and polio as well as pertussis

E

Boostrix- IPV” & “Repevax” are acellular

Question  15.        Which, if any, of the following statements are true in relation to the JCVI’s advice of the best time to administer pertussis vaccine in pregnancy?

A

20 - 24 weeks

B

25- 28 weeks

C

28 - 32 weeks

D

28 - 34 weeks

E

none of the above

Question  16.        A woman has suspected pertussis in early pregnancy. Should she still be offered vaccination?

A

Yes

B

No

C

I don’t know

D

I hate this subject now

Question  17.        A pregnant woman misses out on vaccination as part of the PIPP. Should vaccination still be offered in the puerperium?

A

Yes

B

No

C

I don’t know

D

I hate this subject now

 

38.   Placenta accreta, increta & percreta.

Abbreviations.

Creta:         term to describe accreta, increta or percreta.

GTG27a:    RCOG’s Green-top Guideline27a: Placenta Praevia and Placenta Accreta: Diagnosis and Management”.

MROP:       manual removal of placenta.

PAS:            placenta accreta spectrum.

PET:            pre-eclampsia.

PIH:            pregnancy-induced hypertension.

TAS:            trans-abdominal ultrasound scan.

TVS:            trans-vaginal ultrasound scan.

Question  1.      Which of the following terms are commonly used for abnormal placental adherence/

invasion?

A.       

a bugger to remove

B.       

abnormally adherent and invasive

C.        

bled like Hell

D.       

morbidly adherent placenta

E.        

morbidly invasive placenta

F.        

placenta accreta spectrum

G.       

none of the above.

Question  2.      Which of the following terms is favoured in GTG27a for abnormal placental

adherence/ invasion?

A.       

a bugger to remove

B.       

abnormally adherent and invasive

C.        

bled like Hell

D.       

morbidly adherent placenta

E.        

morbidly invasive placenta

F.        

placenta accreta spectrum

G.       

none of the above.        

Question  3.      Who is accredited in GTG27a for being the historical source of the definition relating

to PAS? And what observations did they make that echo relevantly today? There is no option list for the second question, which you won’t be asked, but is interesting and may help you to remember stuff.

A.       

Irvine and Berlin

B.       

Irving and Harthog

C.        

Irvine and St. Michael

D.       

Irvine and Beyond

E.        

Irving and Berlin

F.        

Irving Berlin

G.       

Irving & Hertig

Question  4.      Which, if any, of the following are true about the definition of ‘low-lying’ placenta?

A.       

a placenta associated with the birth of a child destined to be an actor specialising in roles as a ‘baddie’ in cowboy films.

B.       

a placenta within 50 mm of the internal os.

C.        

a placenta within 20 mm of the internal os.

D.       

a placenta within 10 mm of the internal os.

E.        

a placenta within 10 miles of the South Pole.

F.        

a placenta that reaches, but does not cover the internal os.

G.       

a placenta that covers the internal os, but not when it is fully dilated.

H.       

none of the above

Question  5.      Which, if any, of the following are true about the definition of placenta previa?

A.       

a placenta within 50 mm of the internal os.

B.       

a placenta within 20 mm of the internal os.

C.        

a placenta within 10 mm of the internal os.

D.       

a placenta that reaches, but does not cover the internal os.

E.        

a placenta that covers the internal os.

F.        

a placenta that covers the internal os, but not when it is fully dilated.

G.       

none of the above

Question  6.      What is the approximate incidence of placenta previa at term?

A.       

1 in   50

B.       

1 in 150

C.        

1 in 200

D.       

1 in 250

E.        

1 in 500

F.        

1 in 750

G.       

1 in 1,000

Question  7.      Which of the following is true about abnormal placental adherence / invasion?

A.       

the diagnosis is dependent on the amount of cursing done by the obstetrician

B.       

the diagnosis is clinical

C.        

the diagnosis is conditional

D.       

the diagnosis is empirical

E.        

the diagnosis is hearsay

F.        

the diagnosis is histological

G.       

none of the above

Question  8.      Choose the best option from the option list for the definition of placenta accreta.

A.       

Placenta which is difficult to remove, but can be separated digitally

B.       

Placental villi invade the decidua, but not the myometrium

C.        

Placental villi attach to the superficial myometrium but do not invade deeper

D.       

Placental villi attach to the superficial myometrium, do not invade deeper and there is no decidua between the villi and myometrium

E.        

Placental villi invade the decidua, myometrium and serosa

F.        

Placental villi invade adjacent organs, e.g. the bladder

Question  9.      Choose the best option from the option list for the definition of placenta increta.

A.       

Placenta is difficult to remove, but can be separated digitally

B.       

Placental villi invade the decidua, but not the myometrium

C.        

Placental villi invade the myometrium but not the serosa

D.       

Placental villi invade the decidua, myometrium and serosa

E.        

Placental villi invade adjacent organs, e.g. the bladder

Question  10.  Choose the best option from the option list for the definition of placenta percreta.

A.       

Placenta which is difficult to remove, but can be separated digitally

B.       

Placental villi invade the myometrium and reach the serosa

C.        

Placental villi invade the myometrium and serosa

D.       

Placental villi invade the myometrium the serosa and may invade adjacent organs, e.g. the bladder

E.        

Placental villi invade adjacent organs, e.g. the bladder

Question  11.  What is the approximate incidence of placenta creta in the UK?

A.       

1-2 per   1,000 deliveries

B.       

1-2 per   1,000 maternities

C.        

1-2 per   5,000 deliveries

D.       

1-2 per   5,000 maternities

E.        

1-2 per 10,000 deliveries

F.        

1-2 per 10,000 maternities

Question  12.  You need to be able to define “maternity”. What is a “maternity”?

A.       

Any pregnancy, including ectopic pregnancy and miscarriage

B.       

Any pregnancy, excluding termination of pregnancy

C.        

Any pregnancy resulting in a live birth

D.       

Any pregnancy resulting in live birth or stillbirth

E.        

Any pregnancy ending from 24 completed weeks plus any resulting in a live birth.

Question  13.  Why is the term “maternity” important?

A.       

We should take best possible care of our pregnant patients

B.       

It is used as the denominator in calculations of the maternal mortality rate

C.        

It is used as the numerator in calculations of the maternal mortality rate

D.       

It is used as the denominator in calculations of the maternal mortality ratio

E.        

It is used as the numerator in calculations of the maternal mortality ratio

Question  14.  This question relates to risk factors for placenta accreta. Match each of the risk

factors listed below with an adjusted odds ratio from the Option List. Each option can be used once, more than once or not at all. Note that some of the adjusted odds ratios show a reduced risk.

Risk factors and adjusted odds ratio.

Risk factor

Adjusted odds ratio

BMI > 30

 

Cigarette smoking in pregnancy

 

Ethnic group non-white

 

IVF pregnancy

 

Maternal age > 35

 

Parity ≥ 2

 

PIH or PET

 

Placenta previa diagnosed pre-delivery

 

Previous Caesarean section > 1

 

Previous Caesarean section x 1

 

Previous uterine surgery – not C. section

 

 

 

 

 

 

 

 

 

 

 

 

 

Option List

Adjusted odds ratio

0.53

0.57

0.66

0.9

1.0

2.0

3.06

3.4

3.48

10

14

16.31

32.13

65.02

102

Question  15.  Placental ‘migration’ is known to occur in a proportion of cases where the placenta is

low-lying, resulting in a normally-sited placenta. Which, if any, of the following statements are true?

A.       

migration occurs in about 90% of cases

B.       

migration occurs in about 80% of cases

C.        

migration occurs in about 70% of cases

D.       

migration occurs in about 60% of cases

E.        

migration occurs in about 50% of cases

F.        

migration occurs in about 40% of cases

G.       

migration occurs in about 30% of cases

H.       

migration occurs in about 20% of cases

I.          

migration occurs in about 10% of cases

J.         

placental migration will cease after Brexit

Question  16.  What is the explanation for the apparent placental ‘migration’ that leads to the

 resolution of low-lying placenta in some cases?

A.       

development of the lower segment

B.       

development of the upper segment

C.        

gravity

D.

↑ liquor volume

E.

↑ ratio of placental: uterine volume

F.

↑ ratio of placental: decidual surface area

G.

↑ ultrasound sensitivity in the 3rd. trimester

H.

none of the above

Question  17.  Which, if any, of the following ultrasound features are markers for ­ risk of PAS?

A.       

hyperechoic areas: ‘lacunae’

B.       

hypoechoic areas: ‘lacunae’

C.        

large feeder vessels to the lacunae

D.

‘moth-eaten’ appearance

E.

‘silkworm-eaten’ appearance

F.

placental bed vascularity increased

G.

none of the above

Question  18.  Why on earth was the lower segment C section developed when section through the

body of the uterus gives better access and keeps away from the ureters and bladder? You might ask why I have included this in an answer or placenta creta and you would have good justification as it has nothing to do with the subject.

Question  19.  Which, if any of the following statements about MRI is true in relation to PAS?

A.       

MRI is superior to US in the diagnosis of PAS

B.       

gadolinium increases the sensitivity and specificity of MRI and is particularly recommended when increta and percreta are suspected

C.        

MRI may be particularly helpful if the placenta is anterior

D.

MRI may be particularly helpful if the placenta is posterior

E.

dark intra-placental bands on T2-weighted scanning suggest PAS

F.

disruption of the utero-placental zone suggests PAS

 

39.   Cervical cancer staging.

Option list.

A

Micro-invasive cervical cancer.

B

Stage IA1

C

Stage IA2

D

Stage IA3

E

Stage IB1

F

Stage IB2

G

Stage IB3

H

Stage IIA

I

Stage IIB

J

Stage IIC

K

Stage IIIa

L

Stage IIIB

M

Stage IIIC

N

Stage IVA

O

Stage IVB

P

Stage IVC

Q

Stage VA

R

Stage VB

S

Stage VC

T

None of the above.

Scenario 1. A woman of 25 has a cone biopsy. The histology report shows squamous cell carcinoma penetrating to a depth of 2 mm and 6 mm in width. The resection margins are tumour-free. There is no evidence of spread outside the uterus. She is nulliparous and wishes to retain her fertility.

Scenario 2. A woman of 25 has a cone biopsy. The histology report shows squamous cell carcinoma penetrating to a depth of 4 mm and 6 mm in width. The resection margins are tumour-free. There is no evidence of spread outside the uterus. She is nulliparous and wishes to retain her fertility.

Scenario 3. A woman of 25 has a cone biopsy. The histology report shows squamous cell carcinoma penetrating to a depth of 5 mm and 6 mm in width. The resection margins are not tumour-free. There is no evidence of spread outside the uterus. She is nulliparous and wishes to retain her fertility.

Scenario 4. A woman of 25 has a cone biopsy. The histology report shows squamous cell carcinoma penetrating to a depth of 6 mm and 3 cm in width. The resection margins are tumour-free. There is no evidence of extension outside the cervix. She is nulliparous and wishes to retain her fertility.

Scenario 5. A woman of 25 has a cone biopsy. The histology report shows squamous cell carcinoma penetrating to a depth of 6 mm and 5 cm in width. The resection margins are tumour-free. She is nulliparous and wishes to retain her fertility.

Scenario 6. A woman of 38 has a cone biopsy. The histology report shows squamous cell carcinoma penetrating to a depth of 4 mm and 6mm in width. The resection margins are tumour-free. An MR scan shows involvement of the lymphatic nodes in the left of the pelvis.

Scenario 7. A woman of 45 has carcinoma of the cervix. It extends into the parametrium, but not to the pelvic sidewall. It involves the upper 1/3 of the vagina. There is MRI evidence of para-aortic node involvement.

Scenario 8. A woman of 55 has carcinoma of the cervix. It extends to the pelvic sidewall. It involves the upper 1/3 of the vagina. She has a secondary on the end of her nose.

Scenario 9. A woman of 55 has carcinoma of the cervix. It involves the bladder mucosa.

Scenario 10. A woman of 35 has a proven cancer of the cervix with extension into the right parametrium, but not to the pelvic sidewall. Left hydroureter and left non-functioning kidney are noted on IVP and there is no other explanation for the findings. Cystoscopy shows bullous oedema of the bladder mucosa.

Scenario 11. A woman of 25 has a cone biopsy. It shows malignant melanoma. The lesion, which was not visible to the naked eye, invades to a depth of 3 mm and is 5 mm in width. The margins of the biopsy are clear. There is evidence of lymphatic vessel involvement. There is no evidence of spread outside the uterus.

 

40. Headache    .

Option list.

1

abdominal migraine

2

analgesia overuse, aka medication overuse

3

bacterial meningitis

4

benign intracranial hypertension

5

BP check

6

cerebral venous sinus thrombosis

7

chest X-ray

8

cluster

9

severe PET / impending eclampsia

10

malaria

11

meningococcal meningitis

12

methyldopa

13

methysergide

14

migraine

15

MRI brain scan

16

nifedipine

17

nitrofurantoin

18

pancreatitis

19

sinusitis

20

subdural haematoma

21

subarachnoid haemorrhage

22

tension

23

ultrasound scan of the abdomen

Scenario 1. A 405-year-old para 3 is admitted at 38 weeks by ambulance with severe headache of sudden onset. She d6escribes it as “the worst I’ve ever had”. Which diagnosis needs to be excluded urgently?

Scenario 2. A 32-year-old para 1 has recently experienced headaches. They are worse on exercise, even mild exercise such as walking up stairs. She experiences photophobia with the headaches. Which is the most likely diagnosis?

Scenario 3. A woman returns from a sub-Saharan area of Africa. She develops severe headache, fever and rigors. What diagnosis should particularly be in the minds of the attending doctors?

Scenario 4. A woman at 37 weeks has s. They particularly occur at night without obvious triggers. They occur every few days.

Scenario 5. A primigravida has had s on a regular basis for many years. They occur most days, are bilateral and are worse when she is stressed. What is the most likely diagnosis?

Scenario 6. A woman complains of recent headaches at 36 weeks. The history reveals that they started soon after she began treatment with a drug prescribed by her GP. Which is the most likely of the following drugs to be the culprit: methyldopa, methysergide, nifedipine or nitrofurantoin?

Scenario 7. A woman is booked for Caesarean section and wishes regional anaesthesia. She had severe headache due to dural tap after a previous Caesarean section. She wants to take all possible steps to reduce the risk of having this again. Which of epidural / spinal anaesthesia has the lower risk of causing dural tap?

Scenario 8. A 25-year-old primigravida attends for her 20-week scan and complains of headache which started two weeks before. There is no significant history. The pain occurs behind her right eye and she describes it as severe and “stabbing” in nature. The pain is so severe that she cannot sit still and has to walk about. She has noticed that her right eye becomes reddened and “watery” during the attack and her nose is “runny”. The attacks have no obvious trigger and mostly occur a few hours after she has gone to sleep. The usually last about 20 minutes. She has no other symptoms. She smokes 20 cigarettes a day but does not take any other drugs, legal or otherwise. What is the most likely diagnosis?

Scenario 9. A woman has a 5-year history of unilateral, throbbing headache often preceded by nausea, visual disturbances, photophobia and sensitivity to loud noise. What is the most likely diagnosis?

Scenario 10. A primigravida is admitted at 38 weeks complaining of headache, abdominal pain and a sensation of flashing lights. What would be the appropriate initial investigation?

Scenario 11. A woman with BMI of 35 attends for her combined Downs syndrome screening test. She complains of pain behind her eyes. The pain is worst last thing at night before she goes to sleep or if she has to get up in the night. She has noticed she has noticed horizontal diplopia on several occasions. She has no other symptoms. Examination shows papilloedema.

Scenario 12. A grande multip of 40 years experienced sudden-onset, severe headache, vomited several times and then collapsed, all within the space of 30 minutes. She is admitted urgently in a semi-comatose state. Examination shows neck-stiffness and left hemi-paresis.

Scenario 13. What did the MMR include as “red flags” for headache in pregnancy? These are not on the option list – you need to dig them out of your head.

Scenario 14. This is not an EMQ. It relates to the incidence of various conditions in women who have migraine. Choose the appropriate arrow for each.

A

asthma

B

developmental dysplasia of the hip in child

C

diabetes

D

Down’s syndrome in child

E

hypertension

F

ischaemic heart disease

G

PET

H

stroke

Scenario 15. Which of the following drugs is contraindicated in the prophylaxis of migraine in pregnancy?

A

amitriptyline

B

ß-blockers

C

ergotamine

D

low-dose aspirin

E

pizotifen

F

pregabalin

G

tricyclic antidepressants

H

verapamil

Scenario 16. Which, if any, of the following statements is true about posterior reversible

encephalopathy syndrome. This is not a true EMQ as there may be > 1 true answer.

Option list.

A

‘thunderclap’ headache is typical

B

‘handclap’ headache is typical

C

classically occurs in the early puerperium and is recurrent

D

classically occurs in the early puerperium and is not recurrent

E

arterial beading is typically seen on MRI

F

arterial beating is typically seen on MRI

G

arterial bleeding is typically seen on MRI

H

venous beading is typically seen on MRI

I

venous beating is typically seen on MRI

J

venous bleeding is typically seen on MRI

K

diagnosis requires lumbar puncture and evidence of CSF pressure

L

treatment is with nimodipine

Scenario 17. Which, if any, of the following statements is true about reversible cerebral

vasoconstriction syndrome. This is not a true EMQ as there may be > 1 true answer.

A

‘thunderclap’ headache is typical

B

‘handclap’ headache is typical

C

classically occurs in the early puerperium and is recurrent

D

classically occurs in the early puerperium and is not recurrent

E

arterial beading is typically seen on MRI

F

arterial beating is typically seen on MRI

G

arterial bleeding is typically seen on MRI

H

venous beading is typically seen on MRI

I

venous beating is typically seen on MRI

J

venous bleeding is typically seen on MRI

K

diagnosis requires lumbar puncture and evidence of CSF pressure

L

treatment is with nimodipine

 

Questions from TOG article by Revell & Moorish. 2014. They are open access.

Red flag features for headaches include:

1.     headache that changes with posture                                                              True / False

2.     associated vomiting                                                                                           True / False

3.     occipital location                                                                                                 True / False

4.     associated visual disturbance.                                                                          True / False

Migraine is classically,

5.     bilateral.                                                                                                               True / False

6.     pulsating.                                                                                                              True / False

7.     aggravated by physical exercise.                                                                      True / False

With regard to migraine headaches in pregnancy,

8.     there is an increase in the frequency of attacks without aura.                  True / False

9.     women who suffer from this have not been shown to have an increase in the risk of pre-eclampsia.                                                                                                                        True / False

10.   the 5HT1-receptor sumatriptan has been shown to be teratogenic.       True / False

11.   women presenting with an aura for the first time are not at an increased risk of intracranial disease.                                                                                                                      True / False

Posterior reversible encephalopathy syndrome,

12.   is associated with an impairment of the autoregulatory mechanism which maintains constant cerebral blood flow where there are blood pressure fluctuations.                        True / False

13.   when it is associated with pre-eclampsia, management should follow the pathway for managing severe pre-eclampsia.                                                                     True / False

With regard to cerebral venous thrombosis,

14.   the incidence in western countries in pregnancy ranges from 1 in 2500 deliveries to 1 in 10 000 deliveries.                                                                                                            True / False

15.   the greatest risk in pregnancy is mainly in the last four weeks.               True / False

16.   the most common site is the sagittal sinus.                                                  True / False

17.   a plain computed tomography is a highly sensitive investigation.            True / False

18.   T2-weighted magnetic resonance imaging has been shown to have limited value in diagnosis.

True / False

19.   the outcome is better when it is associated with pregnancy and the puerperium compared to that occurring outside pregnancy.                                                                             True / False

20.   when it occurs in pregnancy, it is a contraindication for future pregnancies.            True / False

 

 

 


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