Thursday 30 June 2011

Tutorial 30 June 2011

Podcast.
Website.
I bought some new equipment this week to try to improve the quality of the sound.
Let me know if you think it is better.

Tonight we tackled 4 essay topics.
Question 1.
A 16-year-old virgin is referred with dysmenorrhoea. You are the SpR and see her in the gynaecology clinic. She is accompanied by her mother.
a.            justify the history you will take.                             8 marks
b.            justify the investigations you will arrange.               4 marks
c.             critically evaluate your management.                     8 marks.

Question 2.
With regard to ovarian hyperstimulation syndrome (OHSS):
1. how is OHSS graded?                                             4 marks.
2. what is the aetiology of OHSS?                                2 marks.
3. how may the incidence of OHSS be reduced?          6 marks.
4. justify your management of a case of OHSS.             8 marks.            

Question 3.
You are the SpR in the antenatal clinic. The consultant is absent due to illness and no other consultant is available. A midwife asks you to see a woman whose scan has shown anencephaly.
1. What steps will you take before seeing the woman?         6 marks
2. Justify the approach you will use during the interview.     10 marks
3. What will you do when the interview is over?                   4 marks         

Question 4.
With regard to uterine rupture:
1. how is uterine rupture graded?                                  2 marks
2. critically evaluate the risk factors for uterine rupture.  6 marks
3. critically evaluate the diagnosis of uterine rupture.      6 marks     
4, outline the management.                                            6 marks                         
                                                               
 As usual, send me your essays and I'll send whatever I manage to get time to write.

Monday 27 June 2011

Tutorial 27 June

Podcast.
Website.
We started with 4 essays.
One had been done before - the ten top recommendations. I just put it in again to remind everyone of its importance.
And John told us that a similar essay to the one on DVT had appeared in the last exam.
When I checked, I found that I had looked into a list of exam questions that has not been updated!
It won't do any harm reviewing this topic as it will come somewhere.
Question 1.
A 35-year-old woman presents to A&E at 8 weeks’ gestation with left calf pain and leg swelling. Deep vein thrombosis is suspected.
1. critically evaluate the immediate management.           8 marks
2. critically evaluate the management of the remainder of the pregnancy and delivery.
                                                                                   8 marks                                                          
3. critically evaluate the advice you will give postnatally. 4 marks 

Question 2.
A primigravid 25-year-old woman has a routine scan at 20 weeks. Hydrops fetalis is noted. Her blood group is A Rhesus positive.
1.      Ouline the main causes of hydrops fetalis at this gestation.                                   12 marks.
2.      Outline the management in particular the management of treateable causes.    8 marks.

Pregnancy. Hydrops. Non-immune at 20 weeks. Primip.
September
1999

Question 3.
List then critically evaluate the ten top recommendations from the recent maternal mortality report.

Question 4.
A 20-year-old woman is referred to the gynaecology clinic with a complaint of hirsutism. Critically evaluate the management.
1.  Outline the necessary facts to obtain from the history.    6 marks.
2.  Justify the investigations you would arrange.                                     8 marks.
3.  Outline the key aspects of the management.                                     6 marks.

Hirsutism. 24 years old. C/o excessive hair. Mgt.
September
2002
Hirsutism. Normal hormones
March
2006
Then we had a look at an MCQ that I started to draft this afternoon.
My intention was to include all the key points from the GTG on management of VTE.
I'll try to finish it soon.
It reads as follows:
VTE in pregnancy.
AD:         aortic dissection.
APPT:    activated partial thromboplastin time.
CDU:      compression duplex ultrasound.
CTPA:    computed tomography pulmonary angiogram.
CV:         contrast venography
HIT:        heparin-induced thrombocytopenia.
IVC:        inferior vena cava.
JVP:       jugular venous pressure.
LFT:        liver function tests.
LMWH: low molecular weight heparin.
MRV:     magnetic resonance venography
PE:          pulmonary embolism.
U&E:      urea & electrolytes.
VQS:      ventilation / perfusion lung scanning.
VTE:       venous thrombo-embolism.

a.       VTE is the leading direct cause of maternal death.
b.      leucocytosis may be the only sign of DVT.              
c.       back pain may be a feature of DVT.                        
d.      CDU is the initial investigation of suspected DVT.
e.      if the initial CDU is –ve, anti-coagulants are stopped.
f.        CV is necessary when the CDU is negative in suspected DVT.
g.       CTPA or VQS should be done in all women with suspected PE.
h.      chest x-ray should be done in all women with suspected VTE.
i.         CTPS has > sensitivity and specificity than VQS in suspected PE.
j.        VQS has good negative predictive value in suspected PE.
k.       VQS delivers more radiation to the maternal breast than CPTA.
l.         CPTA delivers more radiation to the fetus that VQS.
m.    VQS is better than CPTA at identifying other pathologies such as AD.
n.      the radiation unit “Gy” is the abbreviation of “Gray”
o.      the radiation unit symbol “Gy” is the abbreviation of “GeigerĪ»”
p.      the ­ risk of breast cancer after VQS has been put at 13.6%.
q.      initial investigation of suspected VTE should include a thrombophilia screen.
r.        initial investigation of suspected VTE should include a coagulation screen.
s.       enoxaparin should be given in a dosage of 175 u./kg. for therapeutic effect.
t.        maternity units should have guidelines for i.v. unfractionated heparin.
u.      regional anaesthesia should not be used until at least 24 hours after stopping therapeutic doses of LMWH.
v.       therapeutic LMWH can be introduced after 3 hours after Caesarean section so long as regional anaesthesia has not been used.
w.     therapeutic LMWH can be introduced after Caesarean section so long as it is at least 6 hours since any epidural catheter.
x.       graded compression stockings should be worn for at least a year after an episode of VTE in pregnancy.

Friday 24 June 2011

Tutorial 23rd. June 2011

Tutorial a.
Tutorial b.
Website.

I somehow managed to record the tutorial in 2 parts and have no way to put them back together. Tutorial a deals with the EMQ discussion. Tutorial b deals with the essay discussion. Perhaps having it in 2 parts will be an improvement - let me know.

The EMQ was as follows. Please attempt to answer before you listen to the discussion or you miss out on the main benefit. E-mail your answer and I'll send mine.

Hepatitis B and pregnancy.
Lead-in.
Each of the following scenarios relates to hepatitis B and pregnancy.
Instructions.
For each scenario, select the most appropriate option from the option list.
Each option can be used once, more than once or not at all.
Abbreviations.
HBcAg:     hepatitis B core antigen
HBeAg:     hepatitis B e antigen         
HBsAg:     hepatitis B surface antigen
HBcAb:     antibody to hepatitis B core antigen
HBeAb:     antibody to hepatitis B e antigen
HBsAb:     antibody to hepatitis B surface antigen
HBIG:       hepatitis B immunoglobulin
HBV:         hepatitis B virus
Scenario 1.
An asymptomatic primigravida books at 10 weeks. Her partner had an acute HBV infection 4 months ago. What results on routine blood testing would indicate that she has an acute infection?
Scenario 2.
An asymptomatic primigravida books at 10 weeks. Her partner had an acute HBV infection 4 months ago. What results on routine blood testing would indicate that she is immune to the HBV as a result of natural infection?
Scenario 3.
An asymptomatic primigravida books at 10 weeks. Her partner had an acute HBV infection 4 months ago. What results on routine blood testing would indicate that she is immune to the HBV as a result of HBV vaccine?
Scenario 4.
An asymptomatic primigravida books at 10 weeks. Her partner had an acute HBV infection 6 months ago. What results on routine blood testing would indicate that she is a chronic carrier of HBV infection?
Scenario 5.
Testing shows that he is positive for HBsAg, positive for HBcAb but negative for IgM HBcAb. What does this mean in relation to his HBV status?
Scenario 6.
Testing shows that he is negative for HBsAg, positive for HBcAb and positive for HBsAb.
What does this mean in relation to his HBV status?
Scenario 7
A primigravid woman at 8 weeks gestation is found to be non-immune to the HBV. She has recently married and her husband is a chronic carrier. What should be done to protect her from infection?
Scenario 8
A woman is a known carrier of Hepatitis B. What is the risk of vertical transmission in the first trimester?
Scenario 9
A woman is a known carrier of Hepatitis B. What is the risk of the neonate who has been infected by vertical transmission in the third trimester becoming a carrier without treatment?
Scenario 10
How effective is hepatitis B prophylaxis in preventing chronic carrier status developing in a neonate infected as a result of vertical transmission?
Scenario 11
Can a woman who is a chronic HBV carrier breastfeed safely?
Scenario 12.
Hepatitis B infection is the most dangerous of the viral hepatitis infections in pregnancy.
Scenario 13.
A pregnant woman who is not immune to HBV has a partner who is a chronic carrier. Can HBV vaccine be administered safely in pregnancy?
Scenario 14.
A pregnant woman who is not immune has a partner with acute hepatitis due to HBV. He cuts his hand and bleeds onto the kitchen table. How should she clean the surface to ensure that she gets rid of the virus?
Scenario 15.
Is it true that the presence of HBeAg in maternal blood is a particular risk factor for vertical transmission? Not really a scenario, but never mind!

Option list.
A.        acyclovir
B.        divorce
C.        HBcAg +ve
D.       HBeAg +ve
E.        HbsAg +ve
F.         HBsAg +ve; HBsAb –ve; HBcAb -ve
G.       HBsAg +ve; HBsAb –ve on two tests six months apart
H.       HBsAG –ve; HBsAb -ve on two tests six months apart
I.          HBsAg –ve; HBsAb +ve; HBcAb –ve
J.          HBsAg –ve; HBsAb +ve; HBcAb +ve
K.        HBsAg –ve; HBsAb +ve
L.         HBsAg +ve; HBcAg +ve
M.     HBV vaccine.
N.       HBIG
O.       HBV vaccine + HBIG
P.        immune as a result of infection
Q.       immune as a result of vaccination
R.        not immune
S.         chronic carrier of HBV infection
T.        10%
U.       30%
V.        50%
W.     60%
X.        70 - 90%
Y.        soap and boiling water
Z.        10% dilution of bleach in water
AA.   10% dilution of formaldehyde in alcohol
BB.   ultraviolet irradiation
CC.   yes
DD.  no
EE.    none of the above

The essays were as follows. We only managed to discuss the first two, having taken so long over the EMQ. However, getting our heads round hepatitis B and its various antigens and antibodies was useful as it is bound to feature in the MCQs or EMQs.

Essays 23 June 2011.

Question 1.
Your consultant is on leave. The Secretary gives you an histology report relating to a 24-year-old woman who had suction evacuation for incomplete miscarriage 10 days before. The histology report is diagnostic of a complete hydatidiform mole.
1.  Justify your immediate management.     8 marks
2.  Detail the subsequent management.    12 marks.

Question 2.
A nulliparous 26-year-old woman with cystic fibrosis presents for pre-pregnancy counselling.
1.   Critically evaluate the factors that would lead you to conclude that pregnancy is contraindicated.                 6 marks.
2.   Critically evaluate the advice you would give about the effect of pregnancy on progression of the disease.    2 marks.
3.   Critically evaluate the advice you would give about the effect of the disease on pregnancy.                             4 marks.
4.   Critically evaluate the advice you would give re the management of the pregnancy, labour and delivery.    6 marks.
5.   Justify the advice you would give re the baby and inheritance of cystic fibrosis.                                                                                          
                          2 marks.

Question 3.
You see a 25-year-old primigravida in the antenatal clinic after referral by the community midwife who feels that the uterus is large-for-dates.
1.      Justify your immediate management.                                           6 marks.
2.      Justify the management of the remainder of the pregnancy.   4 marks.
3.      Justify the management of the delivery.                                       6 marks.
4.      Justify the advice you will give post-delivery.                               4 marks.

Question 4.
A 30-year-old nulliparous woman is referred for pre-pregnancy counselling. Her BMI is 40.
1.  Outline the history you will take.                  4 marks.
2.  Justify the investigations you will arrange.  2 marks.
3.  Justify your management.                               6 marks.
4.  Ouline the issues you will discuss with her about the problems linked to obesity in pregnancy.
                                                                                          8 marks.

Monday 20 June 2011

Tutorial 20 June 2011

Podcast.
Website.
Tonight we started with an EMQ and then went on to essays. I have been trying to work through the likely oncology topics. These are a problem unless you are a sub-specialty trainee. You don't have FIGO staging etc. at your fingertips. There is no easy answer. You just have to read it up and put it on your last-minute revision list.
The EMQ was as follows.
Read each of the following clinical scenarios and choose the best management from the list of options. Each option may be used once, more than once or not at all.

A.      anticipate spontaneous vaginal delivery
B.      perform biophysical profile.
C.      perform fetal scalp pH sampling
D.      perform fetal buttock skin pH sampling
E.       arrange flow cytometry to assess for feto-maternal haemorrhage
F.       correct maternal diabetic keto-acidosis and re-assess
G.     exclude cephalo-pelvic disproportion
H.      check for descent with contraction / maternal pushing
I.        give steroids to promote fetal lung maturation.
J.        deploy the APH protocol
K.      start syntocinon
L.       use the Kiwi
M.    use the silastic ventouse
N.     use Kiel land forceps
O.     use Neville-Barnes forceps
P.      use Spencer Wells forceps
Q.     breech extraction
R.      internal podalic version and breech extraction
S.       elective Caesarean section
T.       emergency Caesarean section
U.     Caesarean hysterectomy
V.      resign your post and become a Cistercian monk / nun
W.    None of the above.

1.      A primigravida with a 10 year history of IDDM is admitted at 30 weeks with diabetic ketoacidosis. The fetal heart rate is noted to 160 b.p.m. with loss of beat-to-beat variability and variable, late decelerations. What action will you take in relation to the fetal condition.
2.      A primigravida with a 10 year history of IDDM with good glycaemic control has actively pushing in the second stage of labour for 2 hours. The first stage of labour lasted 8 hours. She has an effective epidural in place. The baby feels of average size and the scan estimate was of a birthweight of 7 – 8lbs. 1/5 of the fetal head is palpable abdominally. The position is OA with the head at the spines and a moderate degree of caput and moulding. What action, if any, will you take to expedite the delivery?
3.      A 35-year-old woman has had two normal deliveries of babies weighing 7 and 8 lb. ten years before. Diabetes has been diagnosed in this pregnancy and has been well-controlled with diet. She is admitted at 39 weeks in spontaneous labour. The cervix is fully dilated and a flexed breech presentation is noted. The fetal heart rate is 100 beats per minute with poor variability and late decelerations. There is thick, fresh meconium. What action, if any, will you take to expedite the delivery?
4.      A 35-year-old primigravida is admitted at 34 weeks with SROM and obvious liquor draining. Abdominal examination shown breech presentation. Her temperature is normal and her condition is good. A CTG shows a normal pattern. What will be your first action?
5.      A 40-year-old woman has had two normal deliveries of babies weighing 7 and 8 lb. ten years before. After a first stage lasting 5 hours she has sudden pain and fresh bleeding. The fetal heart rate drops to 90 beats per minute with no recovery over a period of 5 minutes. The cervix is noted to be almost fully dilated with only a thin rim of cervix anteriorly. The position is OA with the head 2 cm. below the spines. There is minimal caput and moulding. What action will you take to expedite the delivery after sending a midwife to call for help?
6.      A primigravida has spontaneous onset of labour at 40 weeks. The first stage last for 15 hours. After active pushing in the second stage for 2 hours, she is becoming tired. The CTG is normal and the liquor is clear. Abdominal examination shows 1/5 of the fetal head to be palpable. The presenting part is at the ischial spines. The position is occipito-transverse with moderate caput and moulding. There is no descent of the presenting part with contractions and pushing. What action, if any, will you take to expedite the delivery?
7.      A primigravida has spontaneous onset of labour at 40 weeks. The first stage last for 15 hours. After active pushing in the second stage for 2 hours, she is becoming tired. The CTG is normal and the liquor is clear. Abdominal examination shows 0/5 of the fetal head to be palpable. The presenting part is at the ischial spines. The position is occipito-transverse with moderate caput and moulding. There is some descent of the presenting part with contractions and pushing. What action, if any, will you take to expedite the delivery?
8.      A primigravida at 32 weeks has been pushing in the second stage for 90 minutes. The first stage lasted for 6 hours and was of spontaneous onset. Maternal condition is good. You have been summoned as the CTG shows bradycardia, loss of variability and late decelerations. The head is not palpable abdominally and the position is occipito-anterior and the station 1 cm. below the ischial spines. What action, if any, will you take to expedite the delivery?
9.      A woman of 45 years from a traveller family has had 5 normal deliveries of babies weighing from 4 to 4.5kg. The youngest child is 10 years old. She is admitted in advanced labour having had no antenatal care. Examination shows the cervix to be fully dilated with the head presenting 1 cm above the spines in an occipito-anterior position. There is moderate caput and moulding. She is obese, but the fetal head is thought to be 1/5 palpable. There is evidence of fetal compromise with loss of variability and late decelerations. What action, if any, will you take to expedite the delivery?
10.   A woman of 30 years with a history of elective Caesarean section for breech presentation in her only previous pregnancy is in labour after a consultant decision that her wish for VBAC is appropriate. After 6 hours in labour she complains of sudden lower abdominal pain. A small amount of fresh blood is noted. The CTG shows sudden onset of compromise with a rate of 80 beats per minute, loss of variability and variability. What action, if any, will you take to expedite the delivery?

The essays were as follows.
Question 1.
A 35 year-old woman books at 6 weeks. She has noted a left breast mass. Breast cancer is suspected.
1. What is the life-time risk of female breast cancer?        1 mark.
2. How does pregnancy affect the risk of breast cancer?  4 marks.
3. Outline the investigation.                                                5 marks.
4. Critically evaluate the management.                            10 marks.

Question 2.
Critically evaluate HRT in relation to breast cancer.

Question 3.
Outline the FIGO classification system for ovarian cancer and how staging influences treatment.

Question 4.
A woman of 48 is referred with erratic vaginal bleeding for six months. She has had an intra-uterine contraceptive in place for five years. She has occasional hot flushes.
1. Justify the things you will focus on in taking her history.  6 marks
2. Justify the investigations you will perform.                       6 marks
3. Justify the advice you will give.                                         8 marks


Question 1.
Breast cancer & pregnancy has not come but may do so as there is a TOG article from 2010: Volume 12, Issue 3, July 2010, Pages: 186–192.

Question 2.
Breast cancer and HRT came in 2000 and 2004, so could reappear any time, particularly as there was a TOG article in 2010. Volume 12, Issue 3, July 2010, Pages: 155–163.

Question 3.
Outline the FIGO classification system for ovarian cancer and how staging influences treatment.
Ovarian cancer has featured as follows:
Cancer: ovarian. Morbidity of chemotherapy. How to reduce
March
1999
Cancer: ovarian. Objectives of surgery
Sept
1998
Cancer: ovarian: +ve family history. Discuss screening
Sept
2005
There was a TOG article in 2007 on management of early disease. Volume 9, Issue 4, October 2007, Pages: 243–247.

Question 4.
This essay came in 1998. It is one of those difficult “easy” essays in which you have to cover a lot of points.


As usual, send me your versions, written under exam conditions, and I'll send mine - if I have written them.

Thursday 16 June 2011

Tutorial 16 June 2011

Podcast.
Website.
Tonight we managed 3 essay plans and an EMQ. The sound quality is not as good as it was on Monday. I have no idea why as I used the same equipment. However, I am gradually learning a bit about podcasting and the equipment involved and I hope things will improve.
Send your answers and I'll send mine, but remember to do them under exam conditions.
The essays were:
Question 1
With regard to anti-phospholipid syndrome:
1.  outline how the diagnosis is made.     4 marks.
2.  outline the clinical manifestations of anti-phospholipid syndrome. 
                                                                         6 marks.
3.  outline the management.                    10 marks.

Question 2
A woman of 38 is referred to the gynaecology clinic as the tail of her IUCD could not be seen when she recently had a routine cervical smear.
1.  Outline the history you will take.                      6 marks.
2.  Justify the investigations you will arrange.      4 marks.
3.  Justify your management.                                 10 marks.

Question 3
With regard to vulval cancer.
1. Describe the FIGO staging.                6 marks.
2. Critically evaluate screening.            4 marks.
2. Outline the management.                10 marks.

And the EMQ was:
For each of the following scenarios, choose the most appropriate management option from  the option list. Each option can be used once, more than once or not at all.
Option list.
A.        COC taken sequentially
B.        COC taken continuously
C.        NSAID
D.        danazol 100 mg. b.d.
E.         GnRH analogue
F.         Depot Provera
G.       continuous combined HRT
H.        trans-vaginal scan
I.          hysteroscopy
J.          diagnostic laparoscopy with ± tubal patency tests as appropriate
K.        laparoscopy and ablation
L.         laparoscopic ovarian drilling
M.      hysterectomy
N.       hysterectomy + BSO + addback HRT
O.       advise marriage and continuous child-bearing.
P.        refer to an endometriosis specialist.
Q.       none of the above.

Scenario 1.
A 15-year old girl is seen by you in the gynaecology clinic. She has severe dysmenorrhoea. She has tried NSAIDs without benefit.


Scenario 2.
 A 15-year old girl is seen by you in the gynaecology clinic. She has severe dysmenorrhoea. She has tried NSAIDs and the COC without benefit.

Scenario 3.
A 46-year old woman with known endometriosis is referred to the gynaecology clinic with worsening pelvic pain and intermenstrual bleeding.

Scenario 4.
 A 35-year-old woman with known endometriosis is referred to the gynaecology clinic with tenesmus, dyspareunia and tenderness and nodularity of the recto-vaginal septum.

Scenario 5.
A 40-year-old woman attends the gynaecology clinic complaining of disabling dysmenorrhoea despite two laparoscopic procedures to ablate endometriosis involving the pelvis and ovaries. Her family is complete. She is not keen on medical treatment as previous treatments have been ineffective and caused side-effects.

Scenario 6.
A 38-year-old woman with known endometriosis is referred to the gynaecology clinic with dysmenorrhoea, mastalgia and heavy periods. She has been sterilised.

Scenario 7.
A 35-year-old lady complains of pelvic pain and deep dyspareunia. The pain is not cyclical. She has just started a new job and does not want to lose time from work. Her BMI is 35 and she smokes 20 cigarettes daily.