Monday, 13 June 2011

Tutorial 13 June 2011

Website.
Podcast.
Tonight we managed an EMQ and 4 essay plans.
They are below.
Send me your versions and I'll send mine.
The EMQ was written hastily in the half hour or so before the tutorial, so it needs a bit of polish.
 But at least it has some ideas.
Diabetes in pregnancy.
Lead-in.
The following scenarios relate to diabetes in pregnancy.
For each, select the action from the option that best fits the scenario.
Pick one option from the option list.
Each option can be used once, more than once or not at all.

Abbreviations.
ACE:       angiotensin converting enzyme.
ARA:      angiotensin II receptor antagonist.
GDM:    gestational diabetes mellitus.
OGTT:   oral glucose tolerance test.

Scenario 1.
A woman with type II diabetes attends for pre-pregnancy counselling. Her HbA1c is 10.6 %. Her health is good. She last had screening for retinopathy 8 months ago. What is the most important advice you will give?

Scenario 2.
A woman with type II diabetes attends for pre-pregnancy counselling. Her HbA1c is 5.4 %. She last had screening for retinopathy 8 months ago. What advice will you give about retinopathy screening?

Scenario 3.
A 35 year-old para 1 with type II diabetes attends for pre-pregnancy counselling. Her health is good. Her HbA1c is 4.8%. Her pregnancy was 2 years ago and was normal. The baby weighed 3.5 kg. at 40 weeks and is healthy. Her serum creatinine is 125 micromol/ litre.

Scenario 4.
A 35 year-old para 1 with type II diabetes attends for pre-pregnancy counselling. Her health is good. Her HbA1c is 4.8%. Her pregnancy was 2 years ago and was normal. The baby weighed 3.5 kg. at 40 weeks and is healthy. Her GFR is 60 ml./minute. What advice will you give about referral to a nephrologist?

Scenario 5.
A 35 year-old para 1 with type II diabetes attends for pre-pregnancy counselling. Her health is good. Her blood sugar levels are well controlled with diet and metformin. What advice will you give about metformin?

Scenario 6.
A 38 year-old woman attends the booking clinic at 8 weeks. GDM was diagnosed at 34 weeks in the 1st. pregnancy. Despite good glycaemic control, the baby weighed 5.2 kg. and required Caesarean section for delivery after a prolonged 2nd. stage. She is keen to have the earliest possible diagnosis of recurrence.

Scenario 7
A 38 year-old woman attends the booking clinic at 8 weeks. GDM was diagnosed at 34 weeks in the 1st. pregnancy. Despite good glycaemic control, the baby weighed 5.2 kg. and required Caesarean section for delivery after a prolonged 2nd. stage. She is keen to have the earliest possible diagnosis of recurrence but has needle phobia and an aversion to self-monitoring.

Scenario 8
A 25-year-old primigravida books at 10 weeks. Her health is good but her BMI is 28. What screening for hyperglycaemia will you arrange.

Scenario 9
A healthy para 1 books at 10 weeks. She takes a statin because of elevated cholesterol and triglyceride levels. Her blood pressure is 130/85. Otherwise she is well.

Scenario 10
A woman

Scenario 11

Option list.
A.        advise postponement of pregnancy.
B.        normal antenatal care.
C.        refer to a joint diabetic / antenatal clinic.
D.        refer to the next joint diabetic / antenatal clinic.
E.         refer for a diabetic opinion.
F.         refer to a nephrologist.
G.       refer to a clinical psychologist.
H.        arrange referral for screening for diabetic retinopathy.
I.          screen for microalbuminuria.
J.          stop ACE inhibitor / ARA drugs and arrange for safer substitutes.
K.        advise to continue statin.
L.         asvise to stop statin.
M.      prescribe folic acid 5mg. daily and advise HbA1c , 6.1%, if not associated with untoward symptoms.
N.       stop oral hypoglycaemic drug and start insulin.
O.       discuss pros and cons of oral hypoglycaemic drug, but allow her to continue to take it.
P.        arrange fasting plasma glucose level and repeat monthly.
Q.       arrange HbA1c assay and repeat monthly.
R.        arrange a 75 gram OGTT now.
S.         arrange a 75 gram OGTT at 16 weeks
T.         arrange a 75 gram OGTT at 28 weeks.
U.       arrange a 100 gram OGTT now.
V.        arrange a 100 gram OGTT at 16 weeks
W.      arrange a 100 gram OGTT at 28 weeks.
X.        Resign, buy a yacht and sail to Bali.
Y.         none of the above
Question 1.
A healthy, 25-year-old, nulliparous woman books at 8 weeks. She wishes to know what particular advice is relevant to her as she is married to a farmer.
1. outline the history you will take.                   6 marks
2. outline the investigations you will arrange.  4 marks
3. justify the advice you will give.                   10 marks.

Question 2.
A six-year-old girl is referred to the gynaecology clinic with a 2 month history of vaginal discharge.
1. Justify the history you will take.                  5 marks
2. Justify the investigations you will do.          5 marks
3. Critically evaluate the management.        10 marks

Question 3.
Critically evaluate the problems linked to adolescent pregnancy in the UK and the steps that can be taken to reduce its prevalence.

Question 4.
Outline the FIGO classification system for endometrial cancer and how staging influences treatment.



Question 1.
This has not featured in the exam. It would be a killer if it did. If there is a consultant on the exam committee from a farming district, it could feature. I have heard the subject discussed from time to time at conferences over the years and there used to be references to it in Dewhurst. Luesley & Baker has one line in a section pneumonia.
Question 2.
This has not featured in the exam essays but there was a TOG article in 2007. It is fully covered in the MCQs: paper 1, question 23 and paper 11, question 36.
Question 3.
This has not features in the essays, but I remember hearing a presentation on it at the last British Congress and there was a TOG article in 2007.OGRM has had two articles: one on management in 2010 and one of prevention in 2011.
Question 4.
Endometrial cancer turns up every few years, but not in the past 6. It is overdue!
There was a TOG article on the FIGO staging last year.
Cancer: endometrial cancer & HRT
September
1997
Cancer: endometrial hyperplasia. 49. Menstrual problems
March
2001
Cancer: endometrial hyperplasia. Age 50. Abnormal bleeding
March
2004
Cancer: endometrial.
March
2005


Thursday, 9 June 2011

Tutorial 9 June 2011

Podcast.
Website.

Tonight we set out to write 4 essays, but only managed 2. I think I was talking too much!
I would suggest that you write essays, or at least plans, for all 4 and send them to me. I'll then send my versions.
Below the topics are extracts from my table of the essays that have featured in the exam in recent years. These indicate that diabetes is a "hot topic". It has come up every 2 or 3 years since 2000, but not since 2007, so is likely to reappear soon. Add in the recent NICE guidelines and you have a classic "hot topic". Contraception has come even more often, twice a year in 1998 and 1999 and not more than every 2 years since. Alcohol has not featured in the essays but would make a very good subject. The only thing upsetting the arithetic is the reduction of the number of essays.

The topics were:
Question 1.
You are the SpR in the antenatal clinic at 31 weeks. You see a 35-year old woman for review. She has had an abnormal GTT at 30 weeks.
Outline your immediate management.                                                         5 marks.
Outline the management of the remainder of the pregnancy and the delivery.  8 marks.
Outline the subsequent management.                                                         4 marks.
Outline the management of the neonate.                                                     3 marks.

Question 2.
A primigravid woman attends the antenatal booking clinic at 5 weeks’ gestation. She smells strongly of alcohol. She admits to consuming at least ½ bottle of vodka each day.
1.      Critically evaluate the public health advice in the UK about alcohol and pregnancy.
                                                                                                 4 marks.
2.      Critically evaluate screening for alcohol abuse in pregnancy.  4 marks.
3.      Critically evaluate the risks to the fetus and child of the mother who abuses alcohol in pregnancy.                                                                       6 marks.
4.      Justify the management you would arrange for this patient.    6 marks.

Question 3.
Critically evaluate the management of thrombocytopenia in pregnancy.

Question 4.
Critically evaluate the non-contraceptive benefits of hormonal contraception.




Pre-pregnancy counselling. Diabetes. Type 1.
September
2007
Pregnancy. Diabetes. Abnormal GTT at 30 weeks
September
2004
Pregnancy. Diabetes. GTT in early pregnancy. Dubious result.
September
2002
Pregnancy. Diabetes. Outcome to match non-diabetic. How to go about it
March
2000


Contraception. LARC. Long-acting, reversible. Advantages & disadvantages.
March
2009
Contraception. Emergency
March
2007
Contraception. Pill & DVT risk – sister has had DVT
March
2005
Contraception. Pill: breakthrough bleeding
March
2004
Contraception. IUCD. Lost threads. Age 38. Management
September
2003
Contraception. Effect on subsequent fertility
March
1999
Contraception. Emergency. 17. Ist coitus.
September
1999
Contraception. IUCD, Copper. 5 yrs in situ. Occ missed K. Age 47
September
1998
Contraception. Pill. Non-contraceptive advantages
March
1998

Pregnancy. Thrombocytopenia. 28 weeks. Primip
March
2000

Monday, 6 June 2011

Tutorial 6 June 2011

Website: www.drcog-mrcog.info.
Podcast: http://soundcloud.com/drtmcf/tutorial-6-june-2011
Tonight we managed 3 essays but no EMQs.
Question 1.
A 35-year-old woman plans to go to a malarial area of Africa to join her husband who works there. She is 6 weeks pregnant.
Critically evaluate the advice you will give her.

Question 2.
A nulliparous woman of 30 years attends for pre-pregnancy counselling.
Her father is a carrier of the Fragile X premutation.
1.  detail the history you will take.                                                                  6 marks
2.  outline the clinical conditions associated with the Fragile X chromosome.     6 marks.
3.  justify your management.                                                                        12 marks.

Question 3.
A woman of 18 attends the A&E Department requesting emergency contraception.
You have been asked to see her.

1.  Outline the history you will take.                                                                4 marks.
2.  Justify the investigations you will arrange.                                                   2 marks.
3.  Outline the methods of emergency contraception and their pros and cons.    8 marks.
3.  Justify your management.                                                                         8 marks.

Send me your answers and I'll send mine.
Don't waste your time and mine by reading up on the subject and spending an hour writing the essay. In the exam you will not have these luxuries and it is the exam that you are preparing for. Unless you write the essays under exam conditions you will get little or no benefit.
I have not yet written answers to essays 2 & 3, but I'll try to find time in the next day or two.

Friday, 3 June 2011

Tutorial 2nd, June 2011.

Website: www.drcog-mrcog.info

Tonight we did 2 EMQs and 3 essays. If you send your answers, I'll send mine.

EMQ. Ulipristal.
Lead-in.
The following scenarios relate to Ulipristal. For each, select the most appropriate from the option list.
Each option can be used once, more than once or not at all.
Scenario 1.
What type of drug is Ulipristal?
Scenario 2.
How is Ulipristal broken down?
Scenario 3.
What is the half-life of Ulipristal?
Scenario 4.
Which drug may prolong the half-life of Ulipristal?
Scenario 5.
What is the main use of Ulipristal?
Scenario 6.
What is the dose of Ulipristal?
Scenario 7.
What time-scale applies to the licensed use of Ulipristal?
Scenario 8.
What contraceptive advice is given to those using Ulipristal?
Scenario 9.
What specific advice is given to women who are breast-feeding?
Scenario 10.
Can treatment with Ulipristal be repeated within 1 month?
Option list.
GnRH analogue.
Selective serotonin reuptake inhibitor.
19-nortestosterone derived progestagen.
21-hydroxyprogesterone-derived progestagen.
mifepristone derivative.
Selective oestrogen receptor modulator.
Selective progesterone receptor modulator.
Urinary excretion.
Metabolised by renal cytochrome P450 enzyme system.
Metabolised by hepatic cytochrome P450 enzyme system.
30 mg. with dose repeated if vomiting occurs within 3 hours.
100 mg. with dose repeated if vomiting occurs within 3 hours.
150 mg. with dose repeated if vomiting occurs within 3 hours.
phenobarbitone
valium
erythromycin
12 hours.
18 hours.
32 hours.
72 hours.
120 hours.
Depot-contraception.
Depression.
Emergency contraception.
Menorrhagia.
Termination of pregnancy.
Yes.
No.
Maybe.
Continue.
Discontinue for 36 hours.
Discontinue for 72 hours.
May interfere with contraception containing progestagen.
May interfere with contraception containing oestrogen.
No action if LARC being used.

EMQ. PPH.
Lead-in.
The following scenarios relate to post-partum haemorrhage.
For each, select the appropriate answer.
Pick one option from the option list.
Each option can be used once, more than once or not at all.
Scenario 1.
A 34 year-old, para 4 delivers the first twin and bleeds loses 250 ml. of fresh blood. A further 300 ml. is lost after the delivery of the second baby. What is the classification of the bleeding?
Scenario 2.
A 25 year-old nulliparous woman delivers a stillborn baby at 22 weeks. 1,000 ml. of fresh bleeding occurs in the next 2 hours. What is the classification of the bleeding?
Scenario 3.
A 45 year-old primigravid woman is readmitted at 10 weeks post-delivery as she has bled continuously for 3 weeks. What is the classification of the bleeding?
Scenario 4.
A 34 year-old woman passes placental tissue and 500 ml. of fresh blood 14 weeks after delivery of her second child. What is the classification of the bleeding?
Scenario 5.
Which drug is recommended by the GTG for routine use in the active management of the 3rd. stage?
Scenario 6.
By what amount does active management using syntometrine reduce the risk of 1ry. PPH?
Scenario 7.
What is the definition of primary PPH?
Scenario 8.
What is the definition of secondary PPH?
Option list.
Bleeding from the birth canal ≥ 500 ml.
Bleeding from the birth canal ≥ 500 ml. up to 24 hours after delivery of the placenta.
Bleeding from the birth canal ≥ 500 ml. from 24 hours after delivery of the placenta until 6 weeks later.
Bleeding from the birth canal ≥ 1,000 ml. from 24 hours after delivery of the placenta until 6 weeks later.
Bleeding from the birth canal ≥ 500 ml. from 24 hours after delivery of the baby until 12 weeks later.
Bleeding from the birth canal ≥ 1,000 ml. from 24 hours after delivery of the baby until 12 weeks later.
Abnormal bleeding from the birth canal from 24 hours after delivery of the baby until 12 weeks later.
APH.
1ry. PPH.
Major primary PPH.
2ry. PPH.
Syntocinon 5 i.u. i.m.
Syntometrine 5 mg. i.m.
Misoprostol 10 mg. orally.
Gemeprost 40 mg. rectally.
Vasopressin 5 i.u. s.c.
20%
40%
60%
80%
None of the above.

Essay 1.
Critically evaluate waterbirth.

Essay 2.
Critically evaluate asymptomatic bacteruria in pregnancy.

Essay 3.
In relation to cervical cancer:
1.            describe the FIGO staging system.             12 marks.
2.            outline how this impacts on treatment.          8 marks.