Thursday, 6 July 2017

Tutorial 6th. July 2017

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34
EMQ. COC. Starting and missed pills
35
EMQ. Headache
36
EMQ. MgSO4 use in O&G. List all the points you think might get a mark in the exam. Think main headings for uses then key points for each. Think EMQ, SBA and viva.
37
EMQ. Hepatitis B
38
EMQ; Clue cells, koilocytes etc.

Question 34. COC Missed pills. Starting the Pill.
Lead-in.
The following scenarios relate to the combined oral contraceptive (COC) and missed pills.
For each, select the option that best fits the scenario.
Each option can be used once, more than once or not at all.
Abbreviations.
UPSI:     unprotected sexual intercourse.
Option list.
A.        pill that is ≥ 12 hours late.
B.         pill that is > 12 hours late.
C.         pill that is ≥ 24 hours late.
D.        pill that is > 24 hours late.
E.         two missed pills at any time in a single cycle.
F.         the first pill taken in one’s first love affair, now recalled with fond nostalgia for its effectiveness in preventing pregnancy, the Prince having been truly a loathsome toad.
G.        no additional contraception required.
H.        additional contraception required for 7 days.
I.           emergency contraception should be considered.
J.          emergency contraception should be recommended.
K.         take the missed pill immediately, but not if it means 2 pills in one day; no additional contraception needed; pill-free interval as normal.
L.          take the missed pill immediately, even if it means 2 pills in one day; no additional contraception needed; pill-free interval as normal.
M.      take the missed pill immediately, even if it means 2 pills in one day; additional contraception for 7 days; pill-free interval as usual.
N.        take one of the missed pills immediately, discard the other missed pills, use extra contraception for 7 days and discuss emergency contraception with your doctor.
O.        take the missed pills immediately, use extra contraception for 7 days and discuss emergency contraception with your doctor.
P.         continuous combined preparation.
Q.        bi-phasic preparation.
R.         quadriphasic preparation.
S.         cannot be answered from the data given.
T.         none of the above.
Scenario 1.
What is the definition of a missed pill?
Scenario 2.
What is the definition of two missed pills?
Scenario 3.
A COC is begun on day 1 of menstruation. What advice should be given about temporary additional contraception?
Scenario 4.
A COC is begun 5 days after day 1 of menstruation. What advice should be given about temporary additional contraception?
Scenario 5.
A COC is begun for the first time on day 1 of menstruation. The fifth pill is missed. What advice should be given?
Scenario 6.
A pill is missed on day 14 of a 21-day pack. What advice should be given?
Scenario 7
A pill is missed on day 21 of a 21-day pack. What advice should be given?
Scenario 8
Two pills are missed in the first week of a 21-day pack. What advice should be given?
Answer:
Scenario 9
Two pills are missed in the second week of a 21-day pack. What advice should be given?
Scenario 10
Two pills are missed in the third week of a 21-day pack. What advice should be given?
Scenario 11
What kind of preparation is Qlaira?
Scenario 12
What advice does the FSRH give in relation to CHC use by women who are breastfeeding?
Option list.
A.       
UKMEC 1
B.       
UKMEC 1 until 6 weeks then UKMEC 2
C.       
UKMEC 2 until 6 weeks then UKMEC 1
D.       
UKMEC 3
E.        
UKMEC 4
Scenario 13
At what age does the FSRH advise that women should stop using CHC?
Pick the statement from the option list that best reflects the FSRH’s advice
Option list.
F.        
there is no age limit if the woman has no risk factors for VTE or medical contraindications
G.       
the age limit is 50 if the woman has no risk factors for VTE or medical contraindications
H.       
the age limit is 55 if the woman has no risk factors for VTE or medical contraindications
I.         
contraception is not needed for women ≥ 55 years.
J.         
none of the above
Scenario 14
Add the risk of VTE per 10,000 women years to the right column for each category.
Category
Risk per 10,000 women per year
Reproductive age not using CHC

Pregnancy

Puerperium

CHC progestogens 1

CHC progestogens 2

“Evra” transdermal patch (

“NuvaRing” vaginal ring

Progestogens 1 are: levonorgestrel, norethisterone & norgestimate
Progestogens 1 are: desogestrel, Dienogest, drospirenone, gestodene & nomegestrol
List of possible risks.
Risk per 10,000 women per year
   2
15
29
300-400
500-600
   5 - 7
   6 - 12
   9 - 12
   9 - 15
Scenario 15
What is the risk of death for a woman having a VTE on CHC?
Option list
A.       
0.1%
B.       
   1%
C.       
   2%
D.       
   5%
E.        
 10%

The document has 10 MCQs at the end. As these are picked out as important facts, it is likely that the exam committee will have woven them into EMQs or SBAs, so you should know the answers.
1      The bleed experienced during the pill-free week is a natural menstrual bleed.                      T  F
2      Contraceptive efficacy of the combined transdermal patch (CTP) may be decreased in women weighing >90 kg.                                                                                                                                T  F
3      CHC can be started at any time in the cycle if the clinician is reasonably certain the woman is not pregnant.                                                                                                                                       T  F
4      If switching from the POP to CHC, additional contraceptive protection is not required.          T  F
5      The CTP can be detached for 48 hours before contraceptive efficacy is decreased.                             T  F
6      Lamotrigine affects contraceptive efficacy of CHC.                                                                 T  F
7      The risk of venous thromboembolism (VTE) when using CHC is highest in the first few months of use.                                                                                                                                                     T  F
8      UK Medical Eligibility Criteria for Contraceptive Use states that having a 1st.-degree relative with a history of VTE under the age of 45 years is UKMEC 3.                                                            T  F
9      CHC can be used if there is a family history of breast cancer without genetic mutation.   T  F
10    CHC is not thought to cause weight gain.                                                                                   T  F

Question 35. Headache.
Lead-in.
The following scenarios relate to headache in pregnancy.
Pick one option from the option list.
Each option can be used once, more than once or not at all.
Option list.
1.       abdominal migraine
2.       analgesia overuse headache aka medication overuse headache
3.       bacterial meningitis
4.       benign intracranial hypertension
5.       BP check
6.       cerebral venous sinus thrombosis
7.       chest X-ray
8.       cluster headache
9.       severe PET / impending eclampsia
10.   malaria
11.   meningococcal meningitis
12.   methyldopa
13.   methysergide
14.   migraine
15.   MRI brain scan
16.   nifedipine
17.   nitrofurantoin
18.   pancreatitis
19.   sinusitis
20.   subdural haematoma
21.   subarachnoid haemorrhage
22.   tension headache
23.   ultrasound scan of the abdomen
Scenario 1.
A 40-year-old para 3 is admitted at 38 weeks by ambulance with severe headache of sudden onset. She describes it as “the worst I’ve ever had”. Which diagnosis needs to be excluded urgently?
Scenario 2.
A 32-year-old para 1 has recently experienced headaches. They are worse on exercise, even mild exercise such as walking up stairs. She experiences photophobia with the headaches. Which is the most likely diagnosis?
Scenario 3.
A woman returns from a sub-Saharan area of Africa. She develops severe headache, fever and rigors. What diagnosis should particularly be in the minds of the attending doctors?
Scenario 4.
A woman at 37 weeks has headaches. They particularly occur at night without obvious triggers. They occur every few days.
Scenario 5.
A primigravida has had headaches on a regular basis for many years. They occur most days, are bilateral and are worse when she is stressed. What is the most likely diagnosis?
Scenario 6.
A woman complains of recent headaches at 36 weeks. The history reveals that the headaches started soon after she began treatment with a drug prescribed by her GP. Which is the most likely of the following drugs to be the culprit: 7.            methyldopa, methysergide, nifedipine and Nitrofurantoin?
Scenario 7
A woman is booked for Caesarean section and wishes regional anaesthesia. She had severe headache due to dural tap after a previous Caesarean section. She wants to take all possible steps to reduce the risk of having this again. Which of epidural and spinal  anaesthesia has the lower risk of causing dural tap headache?
Scenario 8
A 25-year-old primigravida complains of headaches which started two weeks before when she attends for her 20 week scan. There is no significant history of previous headache. The pain occurs behind her right eye and she describes it as severe and “stabbing” in nature. The pain is so severe that she cannot sit still and has to walk about. She has noticed that her right eye becomes reddened and “watery” during the attack and her nose is “runny”. The attacks have no obvious trigger and mostly occur a few hours after she has gone to sleep. The usually last about 20 minutes. She has no other symptoms. She smokes 20 cigarettes a day but does not take any other drugs, legal or otherwise. What is the most likely diagnosis?
Scenario 9
A woman has a 5-year history of unilateral, throbbing headache often preceded by nausea, visual disturbances, photophobia and sensitivity to loud noise. What is the most likely diagnosis?
Scenario 10
A primigravida is admitted at 38 weeks complaining of headache, abdominal pain and a sensation of flashing lights. What would be the appropriate initial investigation?
Scenario 11
A woman with BMI of 35 attends for her combined Downs syndrome screening test. She complains of pain behind her eyes. The pain is worst last thing at night before she goes to sleep or if she has to get up in the night. She has noticed she has noticed horizontal diplopia on several  occasions. She has no other symptoms. Examination shows papilloedema.
Scenario 12
A grande multip of 40 years experienced sudden-onset, severe headache, vomited several times and then collapsed, all within the space of 30 minutes. She is admitted urgently in a semi-comatose state. Examination shows neck-stiffness and left hemi-paresis.
Scenario 13.
What did the MMR include as “red flags” for headache in pregnancy? These are not on the option list – you need to dig them out of your head.

Question 36. Magnesium sulphate use in O&G.
MgSO4 use in O&G. List all the points you think might get a mark in the exam. Think of main headings for uses then key points for each. Think EMQ, SBA and viva.

Question 37. Hepatitis B and pregnancy.
Instructions.
For each scenario, select the most appropriate option from the option list.
Each option can be used once, more than once or not at all.
Abbreviations.
CNP:           Handbook of Obstetric Medicine. 5th. Edition. Catherine Nelson-Piercy. CRC Press. 2015. 
HAV:           hepatitis A virus
HBcAg:       hepatitis B core antigen
HBeAg:       hepatitis B e antigen
HBsAg:       hepatitis B surface antigen
HBcAb:       antibody to hepatitis B core antigen
HBeAb:      antibody to hepatitis B e antigen
HBsAb:       antibody to hepatitis B surface antigen
HBIG:         hepatitis B immunoglobulin
HBV:           hepatitis B virus
HBcAg:       hepatitis B core antigen
HBeAg:       hepatitis B e antigen
HBsAg:       hepatitis B surface antigen
HBcAb:       antibody to hepatitis B core antigen
HBeAb:      antibody to hepatitis B e antigen
HBsAb:       antibody to hepatitis B surface antigen
HBIG:         hepatitis B immunoglobulin
HCV:           hepatitis C virus
HEV:           hepatitis E virus
HSV:           herpes simplex virus
VT:              vertical transmission
Option list.
A.       
acyclovir 
B.       
divorce
C.       
HBcAg +ve
D.       
HBeAg +ve
E.        
HbsAg +ve
F.        
HBsAg +ve; HBsAb –ve;  HBcAb –ve; HBeAg +ve
G.       
HBsAg +ve; HBsAb –ve on two tests six months apart
H.       
HBsAg -ve; HBsAb -ve on two tests six months apart
I.         
HBsAg -ve; HBsAb +ve; HBcAb –ve
J.         
HBsAg -ve; HBsAb +ve; HBcAb +ve
K.        
HBsAg -ve; HBsAb +ve
L.        
HBsAg +ve; HBcAg +ve
M.     
HBV vaccine
N.       
HBIG
O.      
HBV vaccine + HBIG
P.        
immune as a result of infection
Q.      
immune as a result of vaccination
R.       
not immune
S.        
chronic carrier of HBV infection
T.        
10%
U.       
30%
V.       
50%
W.     
60%
X.        
70-90%
Y.        
soap and boiling water
Z.        
10% dilution of bleach in water
AA.   
10% dilution of formaldehyde in alcohol
BB.   
ultraviolet irradiation
CC.   
yes
DD.  
no
EE.    
HAV
FF.     
HBV
GG.  
HCV
HH.  
HEV
II.       
HSV
JJ.       
none of the above
Scenario 1.
An asymptomatic primigravida books at 10 weeks. Her partner had an acute HBV infection 4 months ago. What results on routine blood testing would indicate that she has an acute HBV infection?
Scenario 2.
An asymptomatic primigravida books at 10 weeks. Her partner had an acute HBV infection 4 months ago. What results on routine blood testing would indicate that she is immune to the HBV as a result of infection?
Scenario 3.
An asymptomatic primigravida books at 10 weeks. Her partner had an acute HBV infection 4 months ago. What results on routine blood testing would indicate that she is immune to the HBV as a result of HBV vaccine?
Scenario 4.
An asymptomatic primigravida books at 10 weeks. Her partner had an acute HBV infection 9 months ago. What results on routine blood testing would show that she is a chronic carrier of HBV infection?
Scenario 5.
Testing shows that he is positive for HBsAg, positive for HBcAb but negative for IgM HBcAb. What does this mean in relation to his HBV status?
Scenario 6.
Testing shows that he is negative for HBsAg, positive for HBcAb and positive for HBsAb.
What does this mean in relation to his HBV status?
Scenario 7.
How common is chronic HBV carrier status in UK pregnant women?
Scenario 8.
What is the risk of death from chronic HBV carrier status?
Scenario 9.
A primigravid woman at 8 weeks gestation is found to be non-immune to HBV. She has recently married and her husband is a chronic carrier. What should be done to protect her from infection?
Scenario 10.
A woman is a known carrier of HBV. What is the risk of vertical transmission in the first trimester?
Scenario 11.
What is the risk of the neonate who has been infected by vertical transmission becoming a carrier without treatment?
Scenario 12.
Should antiviral maternal therapy in the 3rd. trimester be considered for women with HBeAg or high viral load?
Scenario 13.
How effective is hepatitis B prophylaxis for the neonate in preventing chronic carrier status as a result of vertical transmission?
Scenario 14.
Can a woman who is a chronic HBV carrier breastfeed safely?
Scenario 15.
Hepatitis B infection is the most dangerous of the viral hepatitis infections in pregnancy.
Scenario 16.
A pregnant woman who is not immune to HBV has a partner who is a chronic carrier. Can HBV vaccine be administered safely in pregnancy?
Scenario 17.
A pregnant woman who is not immune has a partner with acute hepatitis due to HBV. He cuts his hand and bleeds onto the kitchen table. How should she clean the surface to ensure that she gets rid of the virus?
Scenario 18.
Is it true that the presence of HBeAg in maternal blood is a particular risk factor for vertical transmission? Not really a scenario, but never mind!
Scenario 19.
Does elective Cs before labour and with the membranes intact reduce the vertical transmission rate?
Scenario 20.
Which hepatitis virus normally produces a mild illness, but represents a major risk to pregnant women, with a mortality rate of up to 5%?
Scenario 21.
A pregnant woman has a history of viral hepatitis and informs the midwife at booking that she is a carrier and that she has a significant risk of cirrhosis and has been advised not to drink alcohol. Which is the most likely hepatitis virus?
Scenario 22.
Which hepatitis virus is an absolute contraindication to breastfeeding after appropriate treatment of the infected mother and prophylaxis for the baby?
Scenario 23.
Which hepatitis virus is linked to an increased risk of obstetric cholestasis?

Question 38. Clue cells, koilocytes etc.
Lead-in.
The following scenarios relate to genital infection.
Pick one option from the option list.
Each option can be used once, more than once or not at all.
Abbreviations.
Ct:                     Chlamydia trachomatis
FPA:                  Family Planning Association
HSV:                 Herpes simplex virus
LGV:                 lymphogranuloma venereum
Ng:                    Neisseria gonorrhoeae
Tv:                    Trichomonas vaginalis
Option list.
A
Actinomyces
B
Bacterial vaginosis
C
Bacteroides
D
Chlamydia trachomatis
E
Chlamydial infection of the genital tract
F
Herpes Simplex
G
Human Papilloma Virus
H
Lymphogranuloma venereum
I
Monilia
J
Neisseria gonorrhoeae
K
Trichomonas vaginalis
Scenario 1.                
Which option or options from the option list best fit with “clue cells”
Scenario 2.                
Which option or options from the option list best fit with “fishy odour”?
Scenario 3.                
Which option or options from the option list best fit with “flagellate organisms”?
Scenario 4.                
Which option or options from the option list best fit with “inflammatory smear”?
Scenario 5.                
Which option or options from the option list best fit with “koilocytes”?
Scenario 6.                
Which option or options from the option list best fit with “non-specific urethritis in the male”?
Scenario 7.                
Which option or options from the option list best fit with “strawberry cervix”?
Scenario 8.                
Which option or options from the option list best fit with “thin grey/ white discharge”?
Scenario 9.                
Which option or options from the option list best fit with “white, curdy discharge”?
Scenario 10.            
Which option or options from the option list best fit with “frothy yellow discharge”?
Scenario 11.            
Which option or options from the option list best fit with “protozoan”?
Scenario 12.            
Which option or options from the option list best fit with “obligate intracellular organism”?
Scenario 13.            
Which option or options from the option list best fit with “blindness”?
Scenario 14.            
Which option or options from the option list best fit with “LGV”?
Scenario 15.            
Which option or options from the option list best fit with “multinucleated cells”?
Scenario 16.            
Which option or options from the option list best fit with “serotypes D–K”?
Scenario 17.            
Which option or options from the option list best fit with “serovars L1-L3”?
Scenario 18.            
Which of the following are true in relation to Amsel’s criteria?
A
used for the diagnosis of bacterial vaginosis
B
used for the diagnosis of trichomonal infection
C
clue cells present on microscopy of wet preparation of vaginal fluid
D
flagellate organism present on microscopic examination of vaginal fluid
E
pH ≤ 4.5
F
pH > 4.5
G
thin, grey-white, homogeneous discharge present
H
frothy, yellow-green discharge present
I
fishy smell on adding alkali (10%KOH)
J
fishy smell on adding acid (10%HCl)
K
koilocytes present
L
absence of vulvo-vaginal irritation
Scenario 19.            
Which of the following are true in relation to Nugent’s Amsel’s criteria?
A
used for the diagnosis of bacterial vaginosis
B
used for the diagnosis of trichomonal infection
C
clue cells present on microscopy of wet preparation of vaginal fluid
D
pH ≤ 4.5
E
pH > 4.5
F
count of lactobacilli
G
count of Gardnerella and Bacteroides
H
count of white cells
Scenario 20.            
Garnerella vaginallis can be cultured from the vagina of what proportion of normal women?
A
< 10%
B
11 - 20%
C
21 - 30%
D
31 - 40%
E
41 - 50%
F
> 50%



1 comment:

  1. how can i find keys to these questions to correct myself.

    ReplyDelete