Thursday 16 July 2020

Tutorial 16th. July 2020






Role-play. Difficult patient. Wants to see the consultant.
55
Structured conversation. Air travel in pregnancy.
56
EMQ. Zika virus & pregnancy.
57
EMQ; APH. Antepartum haemorrhage.


54. Candidate’s instructions.
You are an ST5 and are in the gynaecology clinic. A patient has been aggressive towards the reception and nursing staff, insisting that she must see the consultant, not a junior doctor. She shouted at both the receptionist and the nurses, saying: ‘I want to see the organ grinder, not the bloody monkey’.
The consultant says that she has no intention of seeing her and that you need to learn to deal with difficult patients.

55. Structured conversation. Air travel in pregnancy. .
Candidate’s instructions.
This is a viva station about air travel & pregnancy. The examiner will ask you 15 questions..
When you have finished a question, you will not be allowed to return to it as later questions may indicate the answer. If you return, no marks will be awarded, even for correct answers.
Question 1.
The RCOG’s Scientific Impact Paper 1 was about air travel and pregnancy. What was its assessment of the quality of the available evidence on the subject? There is no option list.
Question 2.
What maternal pregnancy complications have been linked to ATIP and what is the current thinking about the risk of their occurrence?
Question 3.
Lead-in
Which of the following statements, if any, are true?.
Option List
A.       
there is good evidence that abruption is more common in passengers
B.       
there is good evidence that abruption is more common in flight attendants
C.       
there is good evidence that PPROM is more common in passengers
D.      
there is good evidence that PPROM is more common in flight attendants
E.       
there is good evidence that miscarriage and FDIU are more common in flight attendants
Question 4.
Which conditions are listed in SIP1 as possible contraindications to ATIP. There is no option list.
Question 5.
What fetal and neonatal complications have been linked to ATIP and what is the current thinking about the risk of their occurrence? There is no option list.
Question 6.
Lead-in
When a plane has reached cruising altitude, approximately what altitude does the cabin pressure equate to?
Option List
A.       
1,000 feet
B.       
3,000 feet
C.       
6,000 feet
D.      
10,000 feet
E.       
20,000 feet
Lead-in
Option List


A.       
5%

B.       
10%

C.       
15%

D.      
20%

E.       
25%

Question 8.
Lead-in
Which of the following conditions are likely to lead to problems as a result of the reduced oxygen saturation at cruising altitudes?
Option List
A.       
anaemia: Hb < 9 g/dl
B.       
women with sickle cell disease
C.       
women with recent gastro-intestinal tract surgery involving bowel sutures
D.      
women with recent urinary tract surgery involving sutures to the bladder
E.       
none of the above
Question 9.
Lead-in
What is the reduction in a passenger’s blood oxygen saturation at cruising altitude in a commercial aircraft?
Option List
A.       
5%
B.       
10%
C.       
15%
D.      
20%
E.       
None of the above
Question 10.
Which, if any, of the following statements are true in relation to humidity?
Option List
A.       
air drawn into the plane at cruising altitude has low water content
B.       
humidity at cruising altitude is about 15%
C.       
humidity in most buildings is about 60%
D.      
low humidity at cruising altitude predisposes to dehydration and DVT
E.       
low humidity at cruising altitude may trigger asthmatic attacks
Question 11.
What advice would you give an occasional traveller about the risks from radiation?
Question 12.
What restrictions on gestation are used by most airlines?
Question 13.
What should pregnant women do to reduce the risk of DVT related to air travel.
Question 14.
What general issues should be discussed with a pregnant woman planning a flight?
Question 15.
What advice should be given about seat belts?

TOG: CPD Questions for 2002. Vol 4, Num 4. These are open access, so are reproduced here.

Air travel in pregnancy
The following are considered safe for use in pregnancy:
1.     Hepatitis B vaccine.                                                                                                        True / False
2.     Ciprofloxacine                                                                                                                 True / False
3.     Chloroquine                                                                                                                    True / False
4.     Water purified with iodides                                                                                          True / False
5.     Rabies vaccine                                                                                                                True / False
6.     Mefloquine                                                                                                                     True / False
The following statements regarding air travel in pregnancy are true:
7.     Thromboprophylaxis with low molecular weight heparin is recommended for the majority of pregnant women on long-haul flights                                                                    True / False
8.     Because of the high radiation exposure to the fetus, women should avoid more than a single long-haul trip                                                                                                               True / False
9.     Airlines consistently decline to carry women beyond 36-weeks’ gestation                   True / False
10.   Women with a Hb concentration of <8 g/dl should be advised against travelling    True / False
The following statements are true:
11.   The majority of commercial airlines carry equipment for neonatal resuscitation         True / False
12.   Neonates are automatically covered by their mother's travel insurance policy         True / False
13.   Pregnant women should not pass through airport security machines                 True / False
14.   The children of airhostesses have an increased risk of congenital abnormality       True / False
15.   Air travel does not increase the likelihood of premature labour                                    True / False
Regarding malaria in pregnancy,
16.   travel to malarial areas should be avoided as prophylaxis is contraindicated      True / False
17.   topical insect repellents are contraindicated in pregnancy                                                  True / False
18.   pregnant women are at an increased risk of contracting malaria infection                  True / False
19.   pregnant women taking proguanil should receive additional folic acid supplements    True / False
20.   acute malaria infection is a cause of intrauterine death                                                 True / False

56. Zika virus & pregnancy.

Abbreviations.
CVS:           Congenital Zika Virus Syndrome.

VTR:           vertical transmission rate.
Zv:              Zika virus.   

Question 1.          
What kind of virus is Zika?
A
DNA
B
DNA + RNA during intermediate stage
C
RNA
D
RNA + DNA during intermediate stage
Question 2.          
To which family of viruses does the Zika virus belong?
A
adenoviruses
B
flaviviruses
C
herpesviruses
D
orthomyxoviruses
E
parvoviruses
F
picornaviruses
G
retroviruses
H
togaviruses
Question 3.          
What other human infections are caused by viruses from this family? This is not a proper EMQ: there may be more than one correct answer.
A
bubonic plague
B
chikungunya
C
chicken pox
D
common cold
E
dengue fever
F
hepatitis C
G
Japanese encephalitis
H
malaria
I
San Francisco encephalitis
J
St. Louis encephalitis
K
West Nile virus
L
Yellow fever
Question 4.          
When was the first reported identification of Zika virus infection in an animal and what was the animal?
A
1922 in a hippopotamus
B
1928 is a giraffe
C
1935 in a macaque monkey
D
1947 in a Rhesus negative monkey
E
1950 in a chimpanzee
H
none of the above.
Question 5.          
Why is the virus called “Zika”?
A
it was first described as “zoonosis affecting Intestines, Kidneys and Adrenals”
B
the animal from which it was first isolated was the Zika monkey
C
it was first isolated from a monkey from the Zika area of Zambia
D
it was first isolated from a monkey from the Zika forest in Uganda
E
it was first identified in the Zika laboratory of the CDC
F
it was first identified by Dr Emily Zika, Professor of Virology, Pretoria, S Africa
G
‘Zika’ is the Zulu word for ‘small head’ and the association was 1st. noted in a Zulu baby
Question 6.          
What is the main reservoir of the Zika virus?
A
anteaters
B
horses
C
humans
D
marmosets
E
monkeys
F
parrots
G
rats
Question 7.          
How is the Zika virus transmitted? This is not a true EMQ as there may be > 1 correct answer.
A
Aedes aegypti mosquitos
B
Aedes albopictus: Asian tiger mosquito
C
Anopheles gambiae mosquitos
D
Culex pipiens  mosquitos
E
fleas
F
ticks
G
worms
H
none of the above.
Question 8.          
At what time of day is transmission of infection most likely?
A
afternoon
B
evening
C
morning
D
night
E
mid-morning and mid-afternoon to dusk
F
two hours after sunrise
G
two hours before sunset
H
two hours after sunset
I
two hours after sunrise and two hours before sunset
J
none of the above
Question 9.          
Where do aegypti mosquitoes breed?
Which, if any of the following
A
in large stretches of water with reed beds
B
in water near human habitation
C
in water remote from human habitation
D
in water in human habitations
E
in water with volume > 5 litres
F
in water with volume > 50 litres
G
in water with volume > 500 litres
H
none of the above.
Question 10.      
When did the current interest in the Zika virus and pregnancy begin and why?
A
Brazil reported an in microcephaly with a possible link to maternal Zika infection in 2014
B
Brazil reported an in microcephaly with a possible link to maternal Zika infection in 2015
C
Brazil reported an in microcephaly with a possible link to maternal Zika infection in 2016
D
the CDC reported 3 cases of microcephaly after proven Zika infection in pregnancy in 2014
E
the CDC reported 3 cases of microcephaly after proven Zika infection in pregnancy in 2015
F
the CDC reported 3 cases of microcephaly after proven Zika infection in pregnancy in 2016
H
none of the above
Question 11.      
How did the WHO categorise the problem and when?
A
Public Health Emergency of International Concern 2015
B
Public Health Emergency of International Concern 2016
C
Public Health Emergency of International Concern 2017
D
Public Health Emergency of International Concern 2018
E
none of the above
Question 12.      
Is Zika virus infection a notifiable condition in the UK?
A
No
B
Yes, but only if people have returned from an area with a high prevalence of Zika
C
Yes, but only if the woman and her partner have returned from an area with high prevalence of Zika
D
Yes, but only if fetal damage has occurred.
E
none of the above
Question 13.      
How is the risk of getting a Zika virus infection from travelling to a particular country categorised? Which, if any, of the following feature?
A
frightful
B
high
C
low
D
moderate
E
scary
F
none of the above
Question 14.      
How long does it take for symptoms of Zika infection to develop?
A
1 – 5 days
B
1 – 7 days
C
2 – 5 days
D
2 – 7 days
E
2 – 10 days
F
3 – 7 days
G
3 – 12 days
H
5 – 10 days
Question 15.      
How long do symptoms of Zika infection last?
A
1 – 5 days
B
1 – 7 days
C
2 – 5 days
D
2 – 7 days
E
2 – 10 days
F
3 – 7 days
G
3 – 12 days
H
5 – 10 days
Question 16.      
What are the most common symptoms of Zika infection? There is no option list – write what you think.
Question 17.      
Is Zika infection more severe in pregnancy?
A
No
B
Yes
Question 18.      
What abnormalities have been associated with Congenital Zika Virus Syndrome? There is no option list, just write as many as you can think of.
Question 19.      
What is thought to be the significance of head circumference at birth in babies whose Hc is in the normal range?
A
higher Hc is associated with cognitive scores
B
higher Hc is associated with language scores
C
lower Hc is associated with cognitive scores
D
lower Hc is associated with language scores
E
Hc is of no significance
F
there is no information on this subject
Question 20.      
What is the approximate risk of vertical transmission of the Zika virus in pregnancy?
A
10%
B
20%
C
30%
D
40%
E
50%
E
the figure is unknown
Question 21.      
Is gestation related to the risk of vertical transmission of the Zika virus? Which, if any, of the following statements are true?
A
evidence is unclear
B
evidence suggests it probably is
C
evidence suggests it probably is not
D
no
E
yes
Question 22.      
What is the risk of adverse fetal outcomes for women proven to have had Zika virus infection?
A
~   5%
B
~ 10%
C
~ 15%
D
~ 20%
E
~ 25%
F
~30%
G
> 30%
H
none of the above
Question 23.      
What advice should be given to a pregnant woman planning to travel to an area with high risk of transmission of Zika infection?
A
consider postponing travel until after the pregnancy
B
don’t go to the area
C
get vaccinated
D
stay indoors from dawn to dusk
E
take chloroquine as prophylaxis
F
take chloroquine + proguanil as prophylaxis
G
take proguanil as prophylaxis
Question 24.      
What advice should be given to a pregnant woman planning to travel to an area with moderate risk of transmission of Zika infection?
A
consider postponing travel until after the pregnancy
B
don’t go to the area
C
get vaccinated
D
stay indoors from dawn to dusk
E
take chloroquine as prophylaxis
F
take chloroquine + proguanil as prophylaxis
G
take proguanil as prophylaxis
Question 25.      
What advice should be given to a woman who decides to travel to an area of high or moderate risk?
There is no option list: jot down everything you think would be relevant.
Question 26.      
A woman returns to the UK from a high-risk Zika area? She develops symptoms suggestive of Zika infection 4 weeks later. What testing should be offered?
A
abdominal ultrasound
B
amniocentesis
C
MR scan
D
no test indicated
E
TVS
F
Zika IgA 
G
Zika IgG 
H
Zika IgG + IgM
I
Zika IgA + IgG + IgM 
J
Zika PCR
Question 27.      
A woman who wishes to be pregnant has returned to the UK from an area of high-risk for Zika infection. Her partner had remained in the UK? What advice should she be given?
A
use barrier contraception for 8 weeks
B
use effective contraception for 8 weeks
C
use barrier contraception + effective contraception for 8 weeks
D
use barrier contraception for 12 weeks
E
use effective contraception for 12 weeks
F
use barrier contraception + effective contraception for 12 weeks
Question 28.      
A man travels to an area with high-risk of Zika infection? On his return to the UK his wife is keen to start a pregnancy. What advice should be given?
A
use barrier contraception for 8 weeks
B
use effective contraception for 8 weeks
C
use effective contraception + barrier contraception for 8 weeks
D
use barrier contraception for 12 weeks
E
use effective contraception for 12 weeks
F
use effective contraception + barrier contraception for 12 weeks
G
use barrier contraception for 6 months
H
use effective contraception for 6 months
I
use effective contraception + barrier contraception for 6 months
J
none of the above.
Question 29.      
A man travels to an area with high-risk of Zika infection for two weeks? During his stay he has symptoms suggestive of Zika infection. His wife is pregnant. What testing should be offered on his return?
A
discuss with local infection specialist
B
discuss with RIPL
C
no test indicated
D
Zika IgG 
E
Zika IgG + IgM
F
Zika IgA + IgG + IgM 
G
Zika PCR
H
none of the above
Question 30.      
A woman is shown to have had a Zika infection? How useful is amniocentesis for assessing the risk to the fetus and determining if an infected fetus in affected?
A
PCR on amniocentesis is the gold standard for diagnosing fetal infection
B
PCR on amniocentesis is of unknown value for diagnosing fetal infection
C
PCR on amniocentesis is of little value for diagnosing fetal infection
D
PCR on amniocentesis is the gold standard for determining the risk of an infected fetus being affected
E
PCR on amniocentesis is of unknown value for determining the risk of an infected fetus being affected
F
PCR on amniocentesis is of little value for diagnosing fetal infection
Question 31.      
What advice and treatment should be offered to the non-pregnant individual with symptoms of Zika infection? This is not a true EMQ as more than one option could be true.
A
adequate fluids
B
acyclovir from GP
C
bed rest for 48 hours
D
emergency contraception
E
get advice from A&E centre
F
offer TOP
G
paracetamol if needed for pain
Question 32.      
A pregnant woman returns from a high-risk Zika area and develops symptoms suggestive of infection? She develops a high fever and is admitted to hospital. What particular things should be done?
A
anticoagulant prophylaxis
B
paracetamol + tepid sponging
C
exclude chikungunya
D
exclude dengue
E
exclude malaria
F
exclude UTI
G
exclude Zika
H
exclude other causes of pyrexial illness
I
offer TOP
J
none of the above
A pregnant woman returns from a high-risk Zika area and develops symptoms suggestive of infection? She develops a high fever and is admitted to hospital. What  should be done in relation to NSAIDs?

A
they should not be used
B
they should not be considered until dengue has been ruled out
C
they should not be considered until malaria has been ruled out
D
the risk of premature closure of the ductus arteriosus rules out their use
E
none of the above.

Question 34.      
A woman with possible Zika exposure has a –ve test for virus antibodies 4 weeks after the last possible exposure. Is this sufficiently long to reassure her that she has not been infected?
A
no
B
yes
C
we don’t know
Question 35.      
A pregnant woman has visited a country with high-risk for Zika exposure but been asymptomatic during her stay and for two weeks on her return? What testing should be offered?
A
baseline ultrasound + repeat at 18-20 weeks
B
baseline ultrasound + repeat at 28-30 weeks
C
baseline ultrasound + repeat at 18-20 weeks + consider repeat at 28-30 weeks
D
amniocentesis
E
MR scan
F
no test indicated
G
Zika IgG 
H
Zika IgG + IgM
I
Zika IgA + IgG + IgM 
J
Zika PCR
Question 36.      
A pregnant woman returns to the UK from an area of high risk for Zika exposure has normal ultrasound scans on her return and at 22 weeks. What further scans, if any, should be arranged? This question is in the exam database.
A
monthly scans
B
scan at 28-30 weeks
C
scan at 32 and 36 weeks
D
scan at 36 weeks
E
no further scans
F
none of the above
Question 37.      
A pregnant woman with possible Zika exposure has an ultrasound scan showing the fetal BPD to be > 2 SDs below the mean for that gestation. What should be done?
A
discuss amniocentesis to confirm fetal infection
B
discuss with the local virologist
C
offer TOP
D
refer to a fetal medicine specialist
E
screen the mother for recent Zika infection
F
none of the above
Question 38.      
A pregnant woman with possible Zika exposure has an ultrasound scan showing significant brain abnormality. What further testing should be discussed?
A
amniocentesis + PCR
B
amniocentesis + RT-PCR
C
MR scan
D
Zika IgG 
E
Zika IgG + IgM
F
Zika IgA + IgG + IgM
G
none of the above

57. Antepartum haemorrhage.
Abbreviations.
ART:     assisted reproduction technology
FGR:     fetal growth restriction
PET:     pre-eclampsia
Option list.
A.       genital tract bleeding ≥ 500 ml. from 24 weeks until the delivery of the baby
B.       genital tract bleeding ≥ 500 ml. from 24 weeks until the delivery of the placenta.
C.       genital tract bleeding ≥ 500 ml. from 24 weeks, or earlier if the baby is live-born, until the delivery of the baby.
D.       1
E.        2
F.        3
G.       4
H.       5
I.         6
J.         7
K.       8
L.        9
M.     10
N.       15
O.      20
P.       30
Q.      50
R.       100
S.        500
T.        1,000
U.       true
V.       false
W.     none of the above
Scenario 1.
What is the definition of APH?
Scenario 2.
What is the upper limit in ml. for minor APH
Scenario 3.
What is the upper limit in ml. of major haemorrhage
Scenario 4.
What is the % risk of recurrence after 1 abruption?
Scenario 5.
What is the % risk of recurrence after 2 abruptions?
Scenario 6.
What is the major risk factor for placental abruption?
Scenario 7
List 10 risk factors for placental abruption.
Scenario 8
List 6 risk factors for placenta previa.
Scenario 9
In what % of pregnancies does APH occur?
Scenario 10
With regards to steps that can be taken to reduce the incidence of APH, what things would you include in a ‘structured conversation’ in the Part 3 exam?



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