Thursday 16 March 2023

Tutorial 16th. March 2023

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16 March 2023.

 

31

EMQ. Hepatitis E

32

Role-play. Premature ovarian insufficiency

33

Viva. Topic TBA during tutorial

34

EMQ. Pertussis

 

31.         EMQ. Hepatitis E.

Question 1.        What is the most common cause of acute viral hepatitis in the UK?

Option list.

A

hepatitis A virus

B

hepatitis B virus

C

hepatitis C virus

D

hepatitis D virus

E

hepatitis E virus

F

herpes simplex virus

G

HIV

Question 2.        Which, if any, of the following are correct about HEV.

Option list.

A

it is a DNA virus

B

it belongs to the genus Hippieviridae

C

it belongs to the genus Hepeviridae

D

it belongs to the genus Hoppieviridae

E

there are six main genotypes

F

genotype 3 is the one of greatest importance in the UK

G

the main reservoir of genotype 3 is intensively-reared chickens

H

the main reservoir of genotype 3 is domestic cats

I

a vaccine exists but is only licensed in Russia

J

none of the above

Question 3.        Which, if any, of the following statements about HEV and pregnancy are true?

Option list.

A

pregnant women are more susceptible to HEV infection

B

pregnant women are more likely to develop serious disease that the non-pregnant

C

the main risk is neonatal death due to vertical transmission

D

the main risk is maternal death

E

the risk of maternal death is highest with infection in the 1st. trimester

F

rates of preterm birth have been reported

G

rates of stillbirth have been reported

 

32.         Role-play. Premature ovarian insufficiency.

Candidate’s instructions.

You are a SpR5 in the gynae clinic and about to see Caroline Faulkner. Your tasks are to take an appropriate history and advise about investigation and management.

GP referral letter.

The Health Centre,

Middle Brook.

Dear Doctor,

Please see Caroline who appears to have an early menopause. Her periods were infrequent for six months or so and she last had one three months ago. She is having some hot flushes. I checked her FSH level and it was reported to be in the menopausal range. I have not dealt with this condition previously and look forward to reading your expert advice.

 

33.         Viva.

The examiner will ask 22 questions about a subject to be revealed during the tutorial.

 

34.         EMQ. Pertussis.

Abbreviations.

JCVI:                    Joint Committee on Vaccination and Immunisation .

PIPP:                   pertussis immunisation programme for pregnancy.

Question  1.      Why is pertussis of current concern in obstetrics?

A

Research has linked pertussis in the 1st. trimester to risk of congenital heart disease

B

A mini-epidemic since 2011 has caused deaths of mothers & of babies < 3 months

C

A mini-epidemic since 2011 has caused deaths of babies < 3 months

D

The infecting organism has become increasingly drug-resistant

E

The infecting organism has become increasingly virulent

Question  2.      Which organism causes whooping cough?

A

Bordella pertussis

B

Bacteroides pertussis

C

Rotavirus whoopoe

D

Respiratory syncytiovirus pertussis

E

None of the above

Question  3.           Which, if any, of the following statements are true about the organism what causes whooping cough? This is not a true SBA as I have condensed several questions into one to save space and there may be more than one correct answer.

A

the organism is aerobic

B

the organism is anaerobic

C

the organism is capsulated

D

the organism is flagellate

E

the organism is an obligate intra-cellular parasite

F

the organism is a Gram -ve diplococcus

G

the organism is a Gram +ve diplococcus

H

the organism requires special transport media

I

no one is going to ask me any of this stuff


Question  4.           Which of the following statements is true?

A

Pertussis is no longer a significant threat to infants

B

Pertussis remains a significant threat to infants

C

The risk of death from pertussis is eliminated by timely antibiotic therapy

D

the risk of death from pertussis is eliminated by timely antiviral therapy

E

None of the above

Question  5.      Which of the following statements is true?

A

Pertussis is not a notifiable disease

B

Pertussis is a notifiable disease

C

Pertussis is not a notifiable disease, but cases should be reported to the local bacteriologist

D

Pertussis is not a notifiable disease, but cases should be subject to audit

Question  6.      What is the main mode of spread of the organism that causes pertussis?

A

contact with contaminated surfaces

B

contaminated food

C

contaminated water

D

respiratory droplets

E

none of the above

Question  7.           What is the main reservoir of the organism that causes pertussis?

A

budgerigars

B

cats

C

dogs

D

humans

E

pigeons

F

pigs

G

none of the above

Question  8.      What is the epidemiology of pertussis?

A

the condition is endemic

B

the condition is endemic with mini-epidemics every 3-5 years

C

the condition is endemic with mini-epidemics most years in the winter months

D

the condition is epidemic, with outbreaks at roughly three-year intervals

E

the condition is epidemic, with outbreaks at unpredictable intervals

Question  9.           What is the incubation period for pertussis?

A

3-6     days

B

7-10   days

C

11-14 days

D

15-18 days

E

none of the above.

Question  10.        What is the duration of infectivity of someone with pertussis?

A

2 days from exposure → 5 days after onset of paroxysms of coughing

B

3 days from exposure → 10 days after onset of paroxysms of coughing

C

4 days from exposure → 14 days after onset of paroxysms of coughing

D

6 days from exposure → 21 days after onset of paroxysms of coughing

E

none of the above

Question  11.        What % of non-immune, close contacts of pertussis will develop the disease?

A

50%

B

60%

C

70%

D

80%

E

90%

Question  12.        Which of the following best describe the DOH’s advice about pertussis? This is not a true SBA as there may be > 1 connect answer.

A

The DOH advises that all pregnant women be immunised to maternal death rates.

B

The DOH advises that all pregnant women be immunised to deaths in babies < 3 months.

C

The DOH advises that all babies be immunised at birth.

D

The DOH advised that “Boostrix- IPV should replace “Repevax” from July 2014.

E

The DOH advises that immunisation of pregnant women be continued permanently

Question  13.        Which, if any, of the following statements is true in relation to average annual number of deaths due to pertussis in the years before routine child immunisation was introduced?

A

the number was 10,000

B

the number was    5,000

C

the number was    4,000

D

the number was    3,500

E

the number was    1,000

Question  14.  Which, if any, of the following statements are true in relation to pertussis vaccine.

A

Boostrix- IPV” is a vaccine for pertussis only

B

“Repevax” is a vaccine for pertussis only

C

Boostrix- IPV” & “Repevax” are live, attenuated vaccines

D

Boostrix- IPV” & “Repevax” act against diphtheria, tetanus and polio as well as pertussis

E

Boostrix- IPV” & “Repevax” are acellular

Question  15.        Which, if any, of the following statements are true in relation to the JCVI’s advice of the best time to administer pertussis vaccine in pregnancy?

A

20 - 24 weeks

B

25- 28 weeks

C

28 - 32 weeks

D

28 - 34 weeks

E

none of the above

Question  16.        A woman has suspected pertussis in early pregnancy. Should she still be offered vaccination?

A

Yes

B

No

C

I don’t know

D

I don’t know

E

I hate this subject now

Question  17.        A pregnant woman misses out on vaccination as part of the PIPP. Should vaccination still be offered in the puerperium?

A

Yes

B

No

C

I don’t know

D

I don’t know

E

I hate this subject now

 

 

 

 


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